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Article Title |
Author(s) |
Type (Status) |
Available Online |
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Regulators of protein metabolism are affected by cyclical nutritional treatments with diets varying in protein and energy content
DOI: 10.1016/j.jnutbio.2011.09.009
Abstract: There is evidence that the E3 ubiquitin ligases muscle ring finger-1 (MuRF1) and atrogin-1, which mediate the ubiquitination of certain proteins and thereby their proteolysis, are regulated ...
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Sourour Boussaid-Om Ezzine,
Sonia Métayer-Coustard,
Anne Collin,
Nicole Rideau,
Christine Leterrier,
Isabelle Bouvarel,
Iban Seiliez,
Sophie Tesseraud
et al.
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Full-length article
(In Press Corrected Proof)
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03 February 2012 |
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PPARγ as a molecular target of EPA anti-inflammatory activity during TNF-α-impaired skeletal muscle cell differentiation
DOI: 10.1016/j.jnutbio.2011.09.005
Abstract: Activated skeletal muscle satellite cells facilitate muscle repair or growth through proliferation, differentiation and fusion into new or existing myotubes. Elevated levels of the proinflam...
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Peter Magee,
Stephen Pearson,
Jayde Whittingham-Dowd,
Jeremy Allen
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Full-length article
(In Press Corrected Proof)
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03 February 2012 |
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Eicosapentaenoic acid and docosahexaenoic acid inhibit macrophage-induced gastric cancer cell migration by attenuating the expression of matrix metalloproteinase 10
DOI: 10.1016/j.jnutbio.2011.09.004
Abstract: Uptake of docosahexaenoic acid (DHA)/eicosapentaenoic acid (EPA) improves the treatment of cancer and reduces tumor-associated macrophage count. However, the mechanism of this relationship i...
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Ming-Hsun Wu,
Yo-Ting Tsai,
Kuo-Tai Hua,
Kun-Che Chang,
Min-Liang Kuo,
Ming-Tsan Lin
et al.
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Full-length article
(In Press Corrected Proof)
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30 January 2012 |
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Resveratrol reduces vascular cell senescence through attenuation of oxidative stress by SIRT1/NADPH oxidase-dependent mechanisms
DOI: 10.1016/j.jnutbio.2011.08.008
Abstract: Objective: Senescence of vascular cells contributes to the development of cardiovascular diseases and the overall aging. This study was undertaken to investigate the effects of resveratrol (...
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Yuhan Tang,
Jian Xu,
Wei Qu,
Xiaolin Peng,
Peng Xin,
Xuefeng Yang,
Chenjiang Ying,
Xiufa Sun,
Liping Hao
et al.
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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The soybean peptide aglycin regulates glucose homeostasis in type 2 diabetic mice via IR/IRS1 pathway
DOI: 10.1016/j.jnutbio.2011.09.007
Abstract: It has been previously reported that aglycin, a natural bioactive peptide isolated from soybean, is stable in digestive enzymes and has an antidiabetic potential. With a view to explore the ...
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Jingli Lu,
Ying Zeng,
Wenrui Hou,
Shasha Zhang,
Lulu Li,
Xiang Luo,
Wei Xi,
Zhengwang Chen,
Ming Xiang
et al.
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Full-length article
(In Press Corrected Proof)
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25 January 2012 |
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Oit1/Fam3D, a gut-secreted protein displaying nutritional status-dependent regulation
DOI: 10.1016/j.jnutbio.2011.09.003
Abstract: Oncoprotein-induced transcript 1 (Oit1) was previously identified as a dietary fat-induced gene in the small intestine of C57Bl/6J mice. In this study, we further characterized Oit1 and its ...
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Nicole J.W. de Wit,
Noortje IJssennagger,
Els Oosterink,
Shohreh Keshtkar,
Guido J.E.J. Hooiveld,
Ronald P. Mensink,
Sebastiaan Hammer,
Johannes W.A. Smit,
Michael Müller,
Roelof van der Meer
et al.
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Full-length article
(In Press Corrected Proof)
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09 January 2012 |
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Coffee polyphenol caffeic acid but not chlorogenic acid increases 5′AMP-activated protein kinase and insulin-independent glucose transport in rat skeletal muscle
DOI: 10.1016/j.jnutbio.2011.09.001
Abstract: Chlorogenic acid is an ester of caffeic and quinic acids, and is one of the most widely consumed polyphenols because it is abundant in foods, especially coffee. We explored whether chlorogen...
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Satoshi Tsuda,
Tatsuro Egawa,
Xiao Ma,
Rieko Oshima,
Eriko Kurogi,
Tatsuya Hayashi
et al.
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Full-length article
(In Press Corrected Proof)
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09 January 2012 |
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Licochalcone E activates Nrf2/antioxidant response element signaling pathway in both neuronal and microglial cells: therapeutic relevance to neurodegenerative disease
DOI: 10.1016/j.jnutbio.2011.07.012
Abstract: Oxidative stress and neuroinflammation are hallmarks of neurodegenerative diseases, which do not play independently but work synergistically through complex interactions exacerbating neurode...
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Sa Suk Kim,
Juhee Lim,
Yeojin Bang,
Jiyeong Gal,
Sang-Uk Lee,
Young-Chang Cho,
Goo Yoon,
Bok Yun Kang,
Seung Hoon Cheon,
Hyun Jin Choi
et al.
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Full-length article
(In Press Corrected Proof)
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09 January 2012 |
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Adipose tissue proteomes of intrauterine growth-restricted piglets artificially reared on a high-protein neonatal formula
DOI: 10.1016/j.jnutbio.2011.09.002
Abstract: The eventuality that adipose tissues adapt to neonatal nutrition in a way that may program later adiposity or obesity in adulthood is receiving increasing attention in neonatology. This stud...
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Ousseynou Sarr,
Isabelle Louveau,
Isabelle Le Huërou-Luron,
Florence Gondret
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Full-length article
(In Press Corrected Proof)
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06 January 2012 |
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Consumption of high-fat diet induces tumor progression and epithelial–mesenchymal transition of colorectal cancer in a mouse xenograft model
DOI: 10.1016/j.jnutbio.2011.07.011
Abstract: Epidemiologic studies suggest that intake of high-fat diet (HFD) promotes colon carcinogenesis. Epithelial–mesenchymal transition (EMT) and inflammation play important roles during tumor pro...
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Feng-Yao Tang,
Man-Hui Pai,
En-Pei Isabel Chiang
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Full-length article
(In Press Corrected Proof)
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06 January 2012 |
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Effects of physiological quercetin metabolites on interleukin-1β-induced inducible NOS expression
DOI: 10.1016/j.jnutbio.2011.08.007
Abstract: Cytokines released by inflammatory cells around the pancreatic islets are implicated in the pathogenesis of diabetes mellitus. Specifically, interleukin-1β (IL-1β) is known to be involved in...
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Jae Min Cho,
Seo-Yoon Chang,
Dong-Bin Kim,
Paul W. Needs,
Yang-Hyeok Jo,
Myung-Jun Kim
et al.
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Full-length article
(In Press Corrected Proof)
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06 January 2012 |
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Curcumin protects against thioacetamide-induced hepatic fibrosis by attenuating the inflammatory response and inducing apoptosis of damaged hepatocytes
DOI: 10.1016/j.jnutbio.2011.08.004
Abstract: Inflammation and hepatic stellate cell (HSC) activation are the most crucial steps in the formation of hepatic fibrosis. Hepatocytes damaged by viral or bacterial infection, alcohol or toxic...
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Mu-En Wang,
Yi-Chen Chen,
I-Shu Chen,
Shu-Chen Hsieh,
Sheng-Shih Chen,
Chih-Hsien Chiu
et al.
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Full-length article
(In Press Corrected Proof)
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05 January 2012 |
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N-3 long-chain polyunsaturated fatty acids inhibit smooth muscle cell migration by modulating urokinase plasminogen activator receptor through MEK/ERK-dependent and -independent mechanisms
DOI: 10.1016/j.jnutbio.2011.08.005
Abstract: Smooth muscle cell (SMC) migration is a major and complex feature of atherosclerosis and restenosis. N-3 long-chain polyunsaturated fatty acids (LCPUFAs) affect SMC migration; however, the m...
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Claire Whyte,
Frank Thies,
Lise Peyrol,
Denis Balcerzak
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Full-length article
(In Press Corrected Proof)
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05 January 2012 |
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Fish oil and 3-thia fatty acid have additive effects on lipid metabolism but antagonistic effects on oxidative damage when fed to rats for 50 weeks
DOI: 10.1016/j.jnutbio.2011.08.006
Abstract: The 3-thia fatty acid tetradecylthioacetic acid (TTA) is a synthetic modified fatty acid, which, similar with dietary fish oil (FO), influences the regulation of lipid metabolism, the inflam...
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Natalya Filipchuk Vigerust,
Daniel Cacabelos,
Lena Burri,
Kjetil Berge,
Hege Wergedahl,
Bjørn Christensen,
Manuel Portero-Otin,
Asgaut Viste,
Reinald Pamplona,
Rolf Kristian Berge,
Bodil Bjørndal
et al.
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Full-length article
(In Press Corrected Proof)
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05 January 2012 |
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Soy peptide-induced stem cell proliferation: involvement of ERK and TGF-β1
DOI: 10.1016/j.jnutbio.2011.08.003
Abstract: This study was conducted to investigate the proliferative effect of vegetable soy peptides on adult stem cells (ASCs) in the absence of serum and their possible mechanisms of action. The pro...
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Jienny Lee,
Kyung-Baeg Roh,
Sang-Cheol Kim,
Jongsung Lee,
Deokhoon Park
et al.
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Full-length article
(In Press Corrected Proof)
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04 January 2012 |
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HuR-mediated posttranscriptional regulation of p21 is involved in the effect of Glycyrrhiza uralensis licorice aqueous extract on polyamine-depleted intestinal crypt cells proliferation
DOI: 10.1016/j.jnutbio.2011.07.009
Abstract: Glycyrrhiza uralensis licorice has long been used worldwide as a food additive and herbal medicine. It possesses a remarkable healing action on gastrointestinal ulcers. The present study was...
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Yi He,
Xian Zhang,
Xing Zeng,
Yu Huang,
Jian-An Wei,
Ling Han,
Cai-Xia Li,
Guo-Wei Zhang
et al.
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Full-length article
(In Press Corrected Proof)
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04 January 2012 |
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Down-regulation of vascular HMGB1 and RAGE expression by n-3 polyunsaturated fatty acids is accompanied by amelioration of chronic vasculopathy of small bowel allografts
DOI: 10.1016/j.jnutbio.2011.08.002
Abstract: Chronic allograft rejection, which is manifested as chronic allograft vasculopathy (CAV), continues to refrain the long-term success of small bowel transplantation (SBTx). The pathway mediat...
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Wei Wei,
Min Chen,
Yanfei Zhu,
Jian Wang,
Ping Zhu,
Yousheng Li,
Jieshou Li
et al.
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Full-length article
(In Press Corrected Proof)
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04 January 2012 |
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Unsaturated fatty acids repress expression of ATP binding cassette transporter A1 and G1 in RAW 264.7 macrophages
DOI: 10.1016/j.jnutbio.2011.07.007
Abstract: Reverse cholesterol transport (RCT), a process to deliver excess cholesterol from the periphery to the liver for excretion from body, is a major atheroprotective property of high-density lip...
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Chai Siah Ku,
Youngki Park,
Sara L. Coleman,
Jiyoung Lee
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Full-length article
(In Press Corrected Proof)
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03 January 2012 |
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Diet-induced obesity elevates colonic TNF-α in mice and is accompanied by an activation of Wnt signaling: a mechanism for obesity-associated colorectal cancer
DOI: 10.1016/j.jnutbio.2011.07.002
Abstract: Inflammation associated with obesity may play a role in colorectal carcinogenesis, but the underlying mechanism remains unclear. This study investigated whether the Wnt pathway, an intracell...
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Zhenhua Liu,
Ryan S. Brooks,
Eric D. Ciappio,
Susan J. Kim,
Jimmy W. Crott,
Grace Bennett,
Andrew S. Greenberg,
Joel B. Mason
et al.
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Full-length article
(In Press Corrected Proof)
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03 January 2012 |
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Abnormal anandamide metabolism in celiac disease
DOI: 10.1016/j.jnutbio.2011.06.017
Abstract: The endocannabinoid system has been extensively investigated in experimental colitis and inflammatory bowel disease, but not in celiac disease, where only a single study showed increased lev...
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Natalia Battista,
Antonio Di Sabatino,
Monia Di Tommaso,
Paolo Biancheri,
Cinzia Rapino,
Francesca Vidali,
Cinzia Papadia,
Chiara Montana,
Alessandra Pasini,
Alberto Lanzini,
Vincenzo Villanacci,
Gino R. Corazza,
Mauro Maccarrone
et al.
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Full-length article
(In Press Corrected Proof)
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03 January 2012 |
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Protective effects of chlorogenic acid against ischemia/reperfusion injury in rat liver: molecular evidence of its antioxidant and anti-inflammatory properties
DOI: 10.1016/j.jnutbio.2011.06.018
Abstract: Hepatic ischemia and reperfusion injury (I/R) is accompanied by excessive reactive oxygen species and resultant sterile inflammation. Chlorogenic acid (CGA), one of the most abundant polyphe...
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Nari Yun,
Jung-Woo Kang,
Sun-Mee Lee
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Full-length article
(In Press Corrected Proof)
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03 January 2012 |
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Nitric oxide mediates low magnesium inhibition of osteoblast-like cell proliferation
DOI: 10.1016/j.jnutbio.2011.06.016
Abstract: An adequate intake of magnesium (Mg) is important for bone cell activity and contributes to the prevention of osteoporosis. Because (a) Mg is mitogenic for osteoblasts and (b) reduction of o...
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Marzia Leidi,
Federica Dellera,
Massimo Mariotti,
Giuseppe Banfi,
Calogero Crapanzano,
Walter Albisetti,
Jeanette A.M. Maier
et al.
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Full-length article
(In Press Corrected Proof)
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03 January 2012 |
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Comparison of intracellular zinc signals in nonadherent lymphocytes from young-adult and elderly donors: role of zinc transporters (Zip family) and proinflammatory cytokines
DOI: 10.1016/j.jnutbio.2011.07.005
Abstract: Intracellular zinc homeostasis is crucial in regulating the inflammatory/immune response at any age. It is tightly regulated by zinc transporters that control influx, efflux and compartmenta...
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Robertina Giacconi,
Marco Malavolta,
Laura Costarelli,
Franco Busco,
Roberta Galeazzi,
Gianni Bernardini,
Nazzarena Gasparini,
Eugenio Mocchegiani
et al.
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Full-length article
(In Press Corrected Proof)
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03 January 2012 |
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A luciferase reporter assay to investigate the differential selenium-dependent stability of selenoprotein mRNAs
DOI: 10.1016/j.jnutbio.2011.07.010
Abstract: The mechanisms regulating the differential selenium (Se)-dependent stability of selenoprotein mRNAs are partially characterized. To further study the Se-dependent regulation of selenoprotein...
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Shuvojit Banerjee,
Siming Yang,
Charles B. Foster
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Full-length article
(In Press Corrected Proof)
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03 January 2012 |
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The citrus flavonone hesperetin inhibits growth of aromatase-expressing MCF-7 tumor in ovariectomized athymic mice
DOI: 10.1016/j.jnutbio.2011.07.003
Abstract: Aromatase is responsible for the rate-determining reaction in estrogen synthesis and is a prime target for treating estrogen-receptor-positive breast cancer. Previous in vitro study has demo...
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Lan Ye,
Franky L. Chan,
Shiuan Chen,
Lai K. Leung
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Full-length article
(In Press Corrected Proof)
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03 January 2012 |
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Trans fatty acids enhance amyloidogenic processing of the Alzheimer amyloid precursor protein (APP)
DOI: 10.1016/j.jnutbio.2011.06.015
Abstract: Hydrogenation of oils and diary products of ruminant animals leads to an increasing amount of trans fatty acids in the human diet. Trans fatty acids are incorporated in several lipids and ac...
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Marcus O.W. Grimm,
Tatjana L. Rothhaar,
Sven Grösgen,
Verena K. Burg,
Benjamin Hundsdörfer,
Viola J. Haupenthal,
Petra Friess,
Stefan Kins,
Heike S. Grimm,
Tobias Hartmann
et al.
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Full-length article
(In Press Corrected Proof)
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03 January 2012 |
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Postweaning low-calcium diet promotes later-life obesity induced by a high-fat diet
DOI: 10.1016/j.jnutbio.2011.07.004
Abstract: The aim of this study was to investigate the effects of a postweaning low-calcium diet on later obesity and explore the underlying mechanisms. Ninety-six male rats were weaned at 3 weeks of ...
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Yong-Han He,
Song-Tao Li,
Yan-Yan Wang,
Guan Wang,
Ying He,
Xi-Lu Liao,
Chang-Hao Sun,
Ying Li
et al.
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Full-length article
(In Press Corrected Proof)
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03 January 2012 |
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Modulation of FoxO1 phosphorylation/acetylation by baicalin during aging
DOI: 10.1016/j.jnutbio.2011.07.008
Abstract: Baicalin is a flavonoid known to modify various redox-related biological activities. Included is its ability to suppress reactive species (RS) producing activity and modulate nuclear factor-...
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Dae Hyun Kim,
Ji Min Kim,
Eun Kyeong Lee,
Yeon Ja Choi,
Chul Hong Kim,
Jae Sue Choi,
Nam Deuk Kim,
Byung Pal Yu,
Hae Young Chung
et al.
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Full-length article
(In Press Corrected Proof)
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30 December 2011 |
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Oleic acid activates peroxisome proliferator-activated receptor δ to compensate insulin resistance in steatotic cells
DOI: 10.1016/j.jnutbio.2011.07.006
Abstract: Nonalcoholic fatty liver disease is frequently associated with type 2 diabetes; however, this idea is challenged by recent studies because hepatic steatosis is not always associated with ins...
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Hung-Tsung Wu,
Wency Chen,
Kai-Chun Cheng,
Po-Ming Ku,
Ching-Hua Yeh,
Juei-Tang Cheng
et al.
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Full-length article
(In Press Corrected Proof)
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30 December 2011 |
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BRCA-1 promoter hypermethylation and silencing induced by the aromatic hydrocarbon receptor-ligand TCDD are prevented by resveratrol in MCF-7 Cells
DOI: 10.1016/j.jnutbio.2011.08.001
Abstract: Epigenetic mechanisms may contribute to reduced expression of the tumor suppressor gene BRCA-1 in sporadic breast cancers. Through environmental exposure and diet, humans are exposed to xeno...
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Andreas J. Papoutsis,
Jamie L. Borg,
Ornella I. Selmin,
Donato F. Romagnolo
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Full-length article
(In Press Corrected Proof)
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26 December 2011 |
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K16-biotinylated histone H4 is overrepresented in repeat regions and participates in the repression of transcriptionally competent genes in human Jurkat lymphoid cells
DOI: 10.1016/j.jnutbio.2011.10.009
Abstract: Holocarboxylase synthetase (HCS) catalyzes the binding of biotin to lysine (K) residues in histones H3 and H4. Histone biotinylation marks are enriched in repressed loci, including retrotran...
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Luisa Rios-Avila,
Valerie Pestinger,
Janos Zempleni
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Full-length article
(In Press Corrected Proof)
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22 December 2011 |
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Prevention of liver ischemia reperfusion injury by a combined thyroid hormone and fish oil protocol
DOI: 10.1016/j.jnutbio.2011.06.004
Abstract: Several preconditioning strategies are used to prevent ischemia–reperfusion (IR) liver injury, a deleterious condition associated with tissue resection, transplantation or trauma. Although t...
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Marcelo Mardones,
Rodrigo Valenzuela,
Pamela Romanque,
Natalia Covarrubias,
Fiorella Anghileri,
Virginia Fernández,
Luis A. Videla,
Gladys Tapia
et al.
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Full-length article
(In Press Corrected Proof)
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05 December 2011 |
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Acute supplementation with eicosapentaenoic acid reduces platelet microparticle activity in healthy subjects
DOI: 10.1016/j.jnutbio.2011.06.006
Abstract: Background: Dietary supplementation with omega-3 fatty acids has been associated with reduced incidence in thrombotic events. In addition, administration of n-3 polyunsaturated fatty acids (...
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Melinda Phang,
Lisa Lincz,
Michael Seldon,
Manohar Lal Garg
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Full-length article
(In Press Corrected Proof)
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02 December 2011 |
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Marginal selenium deficiency down-regulates inflammation-related genes in splenic leukocytes of the mouse
DOI: 10.1016/j.jnutbio.2011.06.011
Abstract: Moderate selenium deficiency may lead to an impaired capacity to cope with health challenges. Functional effects of suboptimal selenium intake are not fully known, and biomarkers for an insu...
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Anna P. Kipp,
Antje Banning,
Evert M. van Schothorst,
Catherine Méplan,
Susan L. Coort,
Chris T. Evelo,
Jaap Keijer,
John Hesketh,
Regina Brigelius-Flohé
et al.
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Full-length article
(In Press Corrected Proof)
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02 December 2011 |
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Epigallocatechin gallate induces expression of heme oxygenase-1 in endothelial cells via p38 MAPK and Nrf-2 that suppresses proinflammatory actions of TNF-α
DOI: 10.1016/j.jnutbio.2011.06.007
Abstract: Epigallocatechin gallate (EGCG), the major polyphenol in green tea, acutely stimulates production of nitric oxide (NO) from vascular endothelium to reduce hypertension and improve endothelia...
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Philomena Pullikotil,
Hui Chen,
Ranganath Muniyappa,
Cynthia C. Greenberg,
Shutong Yang,
Chad E.N. Reiter,
Ji-Won Lee,
Jay H. Chung,
Michael J. Quon
et al.
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Full-length article
(In Press Corrected Proof)
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02 December 2011 |
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l-Arginine stimulates the mTOR signaling pathway and protein synthesis in porcine trophectoderm cells
DOI: 10.1016/j.jnutbio.2011.06.012
Abstract: Impairment of placental growth is a major factor contributing to intrauterine growth retardation (IUGR) in both human pregnancy and animal production. Results of recent studies indicate that...
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Xiangfeng Kong,
Bie Tan,
Yulong Yin,
Haijun Gao,
Xilong Li,
Laurie A. Jaeger,
Fuller W. Bazer,
Guoyao Wu
et al.
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Full-length article
(In Press Corrected Proof)
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02 December 2011 |
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Pretreatment with alanyl-glutamine suppresses T-helper-cell-associated cytokine expression and reduces inflammatory responses in mice with acute DSS-induced colitis
DOI: 10.1016/j.jnutbio.2011.06.002
Abstract: T-helper (Th) cells play a major role in initiating and shaping the pathologic response in inflammatory bowel disease (IBD). Glutamine (GLN) is a nutrient with immune-modulating effects. Thi...
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Chia-Chou Chu,
Yu-Chen Hou,
Man-Hui Pai,
Chen-Jui Chao,
Sung-Ling Yeh
et al.
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Full-length article
(In Press Corrected Proof)
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02 December 2011 |
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The açaí flavonoid velutin is a potent anti-inflammatory agent: blockade of LPS-mediated TNF-α and IL-6 production through inhibiting NF-κB activation and MAPK pathway
DOI: 10.1016/j.jnutbio.2011.06.013
Abstract: Recent studies have shown that some flavonoids are modulators of proinflammatory cytokine production. In this study, velutin, a unique flavone isolated from the pulp of açaí fruit (Euterpe o...
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Chenghui Xie,
Jie Kang,
Zhimin Li,
Alexander G. Schauss,
Thomas M. Badger,
Shanmugam Nagarajan,
Tong Wu,
Xianli Wu
et al.
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Full-length article
(In Press Corrected Proof)
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02 December 2011 |
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Coordinate expression and localization of iron and zinc transporters explain iron–zinc interactions during uptake in Caco-2 cells: implications for iron uptake at the enterocyte
DOI: 10.1016/j.jnutbio.2011.06.008
Abstract: Iron and zinc have diverse and important physiological functions. Yet, the mechanism of their absorption at the intestine remains controversial and is confounded by the fact that many studie...
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Vasuprada Iyengar,
Raghu Pullakhandam,
K. Madhavan Nair
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Full-length article
(In Press Corrected Proof)
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02 December 2011 |
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Resveratrol induces Sirt1-dependent apoptosis in 3T3-L1 preadipocytes by activating AMPK and suppressing AKT activity and survivin expression
DOI: 10.1016/j.jnutbio.2011.06.003
Abstract: Resveratrol is a natural polyphenolic compound with anti-inflammatory, antioxidant and neuroprotective properties, and it serves as a chemopreventive and chemotherapeutic agent. However, onl...
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Sifan Chen,
Xincai Xiao,
Xiang Feng,
Wenxue Li,
Niman Zhou,
Lin Zheng,
Yanshuang Sun,
Zili Zhang,
Wei Zhu
et al.
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Full-length article
(In Press Corrected Proof)
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02 December 2011 |
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Docosahexaenoic acid attenuates macrophage-induced inflammation and improves insulin sensitivity in adipocytes-specific differential effects between LC n-3 PUFA
DOI: 10.1016/j.jnutbio.2011.06.014
Abstract: Objective: Adipose tissue inflammation with immune cell recruitment plays a key role in obesity-induced insulin resistance (IR). Long-chain (LC) n-3 polyunsaturated fatty acids (PUFA) eicosa...
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Elizabeth Oliver,
Fiona C. McGillicuddy,
Karen A. Harford,
Clare M. Reynolds,
Catherine M. Phillips,
Jane F. Ferguson,
Helen M. Roche
et al.
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Full-length article
(In Press Corrected Proof)
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02 December 2011 |
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Lycopene and the LXRα agonist T0901317 synergistically inhibit the proliferation of androgen-independent prostate cancer cells via the PPARγ-LXRα-ABCA1 pathway
DOI: 10.1016/j.jnutbio.2011.06.009
Abstract: In our previous study, we demonstrated that lycopene can inhibit the proliferation of androgen-dependent prostate LNCaP cancer cells through the activation of the peroxisome proliferator-act...
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Chih-Min Yang,
Ya-Ling Lu,
Huei-Yan Chen,
Miao-Lin Hu
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Full-length article
(In Press Corrected Proof)
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02 December 2011 |
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Intrauterine growth restriction leads to changes in sulfur amino acid metabolism, but not global DNA methylation, in Yucatan miniature piglets
DOI: 10.1016/j.jnutbio.2011.06.005
Abstract: Intrauterine growth restriction (IUGR), in both animals and humans, has been linked to metabolic syndrome later in life. There has been recent evidence that perturbations in sulfur amino aci...
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Dylan S. MacKay,
Julie D. Brophy,
Laura E. McBreairty,
Ross A. McGowan,
Robert F. Bertolo
et al.
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Full-length article
(In Press Corrected Proof)
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02 December 2011 |
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Nutritional and supranutritional levels of selenate differentially suppress prostate tumor growth in adult but not young nude mice
DOI: 10.1016/j.jnutbio.2011.06.001
Abstract: The inhibitory effect of oral methylseleninic acid or methylselenocysteine administration on cancer cell xenograft development in nude mice is well characterized; however, less is known abou...
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Alexandra Holmstrom,
Ryan, T.Y. Wu,
Huawei Zeng,
K.Y. Lei,
Wen-Hsing Cheng
et al.
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Full-length article
(In Press Corrected Proof)
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02 December 2011 |
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Treatment with low-dose resveratrol reverses cardiac impairment in obese prone but not in obese resistant rats
DOI: 10.1016/j.jnutbio.2011.06.010
Abstract: We hypothesized that a low-dose resveratrol will reverse cardiovascular abnormalities in rats fed a high-fat (HF) diet. Obese prone (OP) and obese resistant (OR) rats were fed an HF diet for...
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Xavier L. Louis,
Sijo J. Thandapilly,
Suresh K. MohanKumar,
Liping Yu,
Carla G. Taylor,
Peter Zahradka,
Thomas Netticadan
et al.
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Full-length article
(In Press Corrected Proof)
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02 December 2011 |
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The role of fructose-enriched diets in mechanisms of nonalcoholic fatty liver disease
DOI: 10.1016/j.jnutbio.2011.09.006
Abstract: Nonalcoholic fatty liver disease (NAFLD) currently affects 20%–30% of adults and 10% of children in industrialized countries, and its prevalence is increasing worldwide. Although NAFLD is a ...
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Kyoko Nomura,
Toshikazu Yamanouchi
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Review article
(In Press Corrected Proof)
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30 November 2011 |
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Protein restriction during gestation alters histone modifications at the glucose transporter 4 (GLUT4) promoter region and induces GLUT4 expression in skeletal muscle of female rat offspring
DOI: 10.1016/j.jnutbio.2011.05.013
Abstract: Maternal nutrition during pregnancy is an intrauterine factor that results in alteration of the offspring genome and associates with disease risk in the offspring. We investigated the impact...
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Shasha Zheng,
Michelle Rollet,
Yuan-Xiang Pan
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Full-length article
(In Press Corrected Proof)
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14 November 2011 |
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Accelerated skeletal muscle recovery after in vivo polyphenol administration
DOI: 10.1016/j.jnutbio.2011.05.014
Abstract: Acute skeletal muscle damage results in fiber disruption, oxidative stress and inflammation. We investigated cell-specific contributions to the regeneration process after contusion-induced d...
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Kathryn H. Myburgh,
Maria J. Kruger,
Carine Smith
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Full-length article
(In Press Corrected Proof)
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14 November 2011 |
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Puerarin prevents isoprenaline-induced myocardial fibrosis in mice by reduction of myocardial TGF-β1 expression
DOI: 10.1016/j.jnutbio.2011.05.015
Abstract: It has been reported that soy isoflavones could significantly increase peroxisome proliferator-activated receptor α/γ gene expressions, while the activation of peroxisome proliferator-activa...
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Rong Chen,
Jie Xue,
Meilin Xie
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Full-length article
(In Press Corrected Proof)
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14 November 2011 |
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Molecular signature of kappa-carrageenan mimics chondroitin-4-sulfate and dermatan sulfate and enables interaction with arylsulfatase B
DOI: 10.1016/j.jnutbio.2011.05.012
Abstract: The common food additive kappa-carrageenan (κ-CGN) is a sulfated polysaccharide that resembles chondroitin-4-sulfate (C4S) and dermatan sulfate (DS). All have a sulfate group on C4 of a glyc...
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Sumit Bhattacharyya,
Joanne K. Tobacman
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Full-length article
(In Press Corrected Proof)
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14 November 2011 |
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Hind limb suspension and long-chain omega-3 PUFA increase mRNA endocannabinoid system levels in skeletal muscle
DOI: 10.1016/j.jnutbio.2011.05.005
Abstract: Muscle disuse has numerous physiological consequences that end up with significant catabolic metabolism and ultimately tissue atrophy. What is not known is how muscle atrophy affects the end...
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Heather L. Hutchins-Wiese,
Yong Li,
Kevin Hannon,
Bruce A. Watkins
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Full-length article
(In Press Corrected Proof)
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04 November 2011 |
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Inhibitory effects of cocoa tea (Camellia ptilophylla) in human hepatocellular carcinoma HepG2 in vitro and in vivo through apoptosis
DOI: 10.1016/j.jnutbio.2011.05.010
Abstract: Cocoa tea (Camellia ptilophylla), a naturally decaffeinated tea commonly consumed as a healthy beverage in southern China, has been recently found to be a potential candidate for the treatme...
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Xiao-rong Yang,
Yuan-yuan Wang,
Kai-Kai La,
Li Peng,
Xiao-hong Song,
Xiang-gang Shi,
Xiao-feng Zhu,
Ping-chung Leung,
Chun-hay Ko,
Chuang-xing Ye
et al.
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Full-length article
(In Press Corrected Proof)
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24 October 2011 |
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Regulation of protein turnover by l-glutamine in porcine intestinal epithelial cells
DOI: 10.1016/j.jnutbio.2011.05.009
Abstract: l-Glutamine (Gln) plays an important role in sustaining the intestinal mucosal mass of humans and animals. However, the underlying mechanisms are largely unknown. This study tested the hypot...
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Pengbin Xi,
Zongyong Jiang,
Zhaolai Dai,
Xilong Li,
Kang Yao,
Chuntian Zheng,
Yingcai Lin,
Junjun Wang,
Guoyao Wu
et al.
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Full-length article
(In Press Corrected Proof)
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17 October 2011 |
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Green tea extract markedly lowers the lymphatic absorption and increases the biliary secretion of 14C-benzo[a]pyrene in rats
DOI: 10.1016/j.jnutbio.2011.05.007
Abstract: Previously, we have shown that green tea extract (GTE) lowers the intestinal absorption of lipids and lipophilic compounds in rats. This study was conducted to investigate whether GTE inhibi...
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Juyeon Kim,
Sung I. Koo,
Sang K. Noh
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Full-length article
(In Press Corrected Proof)
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14 October 2011 |
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Zinc deficiency exacerbates diabetic down-regulation of Akt expression and function in the testis: essential roles of PTEN, PTP1B and TRB3
DOI: 10.1016/j.jnutbio.2011.05.011
Abstract: Since zinc (Zn) plays an important role in the spermatogenesis and Zn deficiency exacerbated diabetes-induced testicular apoptosis, the present study investigated the effect of Zn deficiency...
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Yuguang Zhao,
Yi Tan,
Junying Dai,
Bo Wang,
Bing Li,
Luping Guo,
Jiuwei Cui,
Guanjun Wang,
Wei Li,
Lu Cai
et al.
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Full-length article
(In Press Corrected Proof)
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14 October 2011 |
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Renal and glycemic effects of high-dose chromium picolinate in db/db mice: assessment of DNA damage
DOI: 10.1016/j.jnutbio.2011.05.004
Abstract: This study examined renal and glycemic effects of chromium picolinate [Cr(pic)3] supplementation in the context of its purported potential for DNA damage. In preventional protocol, male obes...
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Mahmood S. Mozaffari,
Babak Baban,
Rafik Abdelsayed,
Jun Yao Liu,
Hereward Wimborne,
Nancy Rodriguez,
Worku Abebe
et al.
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Full-length article
(In Press Corrected Proof)
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28 September 2011 |
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Adipose triglyceride lipase expression and fasting regulation are differently affected by cold exposure in adipose tissues of lean and obese Zucker rats
DOI: 10.1016/j.jnutbio.2011.05.008
Abstract: Adipose triglyceride lipase (ATGL) hydrolyzes triacylglycerols to diacylglycerols in the first step of lipolysis, providing substrates for hormone-sensitive lipase (HSL). Here we studied whe...
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Antoni Caimari,
Paula Oliver,
Andreu Palou
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Full-length article
(In Press Corrected Proof)
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23 September 2011 |
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A dietary conjugated linoleic acid treatment that slows renal disease progression alters renal cyclooxygenase-2-derived prostanoids in the Han: SPRD-cy rat
DOI: 10.1016/j.jnutbio.2011.04.016
Abstract: A mixture of dietary conjugated linoleic acid (CLA) isomers reduces inflammation and mitigates disease progression in the Han:SPRD-cy rat model of chronic kidney disease. Since cyclooxygenas...
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Andrew P. Wakefield,
Malcolm R. Ogborn,
Naser Ibrahim,
Harold M. Aukema
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Full-length article
(In Press Corrected Proof)
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22 September 2011 |
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Chemopreventive effects of the dietary histone deacetylase inhibitor tributyrin alone or in combination with vitamin A during the promotion phase of rat hepatocarcinogenesis
DOI: 10.1016/j.jnutbio.2011.04.010
Abstract: The chemopreventive effects of tributyrin (TB) and vitamin A (VA), alone or in combination, were investigated during the promotion phase of rat hepatocarcinogenesis. Compared to diethylnitro...
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Aline de Conti,
Joice Kuroiwa-Trzmielina,
Maria A. Horst,
Bruna K. Bassoli,
Carlos E.A. Chagas,
Eduardo Purgatto,
Felicia P. Cavalher,
Anamaria A. Camargo,
Alceu A. Jordão,
Hélio Vannucchi,
Clarissa Scolastici,
Thomas P. Ong,
Fernando S. Moreno
et al.
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Full-length article
(In Press Corrected Proof)
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22 September 2011 |
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Antimetastatic activity of pinosylvin, a natural stilbenoid, is associated with the suppression of matrix metalloproteinases
DOI: 10.1016/j.jnutbio.2011.04.021
Abstract: Metastasis is a major cause of death in cancer patients. Our previous studies showed that pinosylvin, a naturally occurring trans-stilbenoid mainly found in Pinus species, exhibited a potent...
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Eun-Jung Park,
Hyen Joo Park,
Hwa-Jin Chung,
Yoonho Shin,
Hye-Young Min,
Ji-Young Hong,
You-Jin Kang,
Yong-Hyun Ahn,
Jae-Ho Pyee,
Sang Kook Lee
et al.
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Full-length article
(In Press Corrected Proof)
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21 September 2011 |