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Diet-induced obesity elevates colonic TNF-α in mice and is accompanied by an activation of Wnt signaling: a mechanism for obesity-associated colorectal cancer

  • Zhenhua Liu

      Affiliations

    • Vitamins and Carcinogenesis Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    • Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA 02111, USA
    • Tufts Medical Center Cancer Center, Tufts University, Boston, MA 02111, USA
    • Corresponding Author InformationCorresponding author. Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA. Fax: +1 617 556 3234.
    • ,
  • Ryan S. Brooks

      Affiliations

    • Vitamins and Carcinogenesis Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    • ,
  • Eric D. Ciappio

      Affiliations

    • Vitamins and Carcinogenesis Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    • Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA 02111, USA
    • ,
  • Susan J. Kim

      Affiliations

    • Tufts Medical Center Cancer Center, Tufts University, Boston, MA 02111, USA
    • ,
  • Jimmy W. Crott

      Affiliations

    • Vitamins and Carcinogenesis Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    • Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA 02111, USA
    • Tufts Medical Center Cancer Center, Tufts University, Boston, MA 02111, USA
    • ,
  • Grace Bennett

      Affiliations

    • Obesity and Metabolism Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    • Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA 02111, USA
    • ,
  • Andrew S. Greenberg

      Affiliations

    • Obesity and Metabolism Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    • Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA 02111, USA
    • ,
  • Joel B. Mason

      Affiliations

    • Vitamins and Carcinogenesis Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    • Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA 02111, USA
    • Tufts Medical Center Cancer Center, Tufts University, Boston, MA 02111, USA
    • Division of Gastroenterology, Tufts Medical Center, Tufts University, Boston, MA 02111, USA

Received 21 March 2011 ,Revised 28 June 2011 ,Accepted 8 July 2011. Published online 03 January 2012 Corrected Proof

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☆ All authors do not have any conflict of interest.

PII: S0955-2863(11)00218-X

doi: 10.1016/j.jnutbio.2011.07.002

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