The Journal of Nutritional Biochemistry
Volume 22, Issue 6 , Pages 543-553 , June 2011

An increase in liver PPARγ2 is an initial event to induce fatty liver in response to a diet high in butter: PPARγ2 knockdown improves fatty liver induced by high-saturated fat

  • Tomomi Yamazaki

      Affiliations

    • Corresponding Author InformationCorresponding authors. Nutritional Science Program, National Institute of Health and Nutrition, Tokyo 162-8636, Japan. Tel.: +81 3 3203 5725; fax: +81 3 3207 3520.
  • ,
  • Sayaka Shiraishi
  • ,
  • Kyoko Kishimoto
  • ,
  • Shinji Miura
  • ,
  • Osamu Ezaki

      Affiliations

    • Corresponding Author InformationCorresponding authors. Nutritional Science Program, National Institute of Health and Nutrition, Tokyo 162-8636, Japan. Tel.: +81 3 3203 5725; fax: +81 3 3207 3520.

Received 5 December 2009 ,Revised 8 April 2010 ,Accepted 21 April 2010.

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 Grants: This work was supported in part by a grant-in-aid for scientific research (KAKENHI) from the Japanese Ministry of Education, Culture, Sports, Science and Technology (MEXT, Tokyo, Japan) and by a grant-in-aid for the Development of Evaluation and Management Methods for Supply of Safe, Reliable and Functional Food and Farm Produce from the Japanese Ministry of Agriculture, Forestry and Fisheries.

☆☆ Author disclosures: No conflicts of interest are declared.

PII: S0955-2863(10)00114-2

doi: 10.1016/j.jnutbio.2010.04.009

The Journal of Nutritional Biochemistry
Volume 22, Issue 6 , Pages 543-553 , June 2011