The Journal of Nutritional Biochemistry
Volume 22, Issue 5 , Pages 487-494, May 2011

Saturated fat intake and alcohol consumption modulate the association between the APOE polymorphism and risk of future coronary heart disease: a nested case-control study in the Spanish EPIC cohort☆☆

  • Dolores Corella

      Affiliations

    • Genetic and Molecular Epidemiology Unit, Department of Preventive Medicine, University of Valencia, Valencia and CIBER Fisiopatología de la Obesidad y Nutrición, ISCIII, Spain
    • Corresponding Author InformationCorresponding author. Genetic and Molecular Epidemiology Unit, School of Medicine, University of Valencia, 15 46010-Valencia, Spain. Tel.: +34 963864800; fax: +34 963864166.
  • ,
  • Olga Portolés

      Affiliations

    • Genetic and Molecular Epidemiology Unit, Department of Preventive Medicine, University of Valencia, Valencia and CIBER Fisiopatología de la Obesidad y Nutrición, ISCIII, Spain
  • ,
  • Larraitz Arriola

      Affiliations

    • Public Health Department of Gipuzkoa, Basque Government, San Sebastian, CIBER Epidemiología y Salud Pública (CIBERESP), Spain
  • ,
  • María Dolores Chirlaque

      Affiliations

    • Department of Epidemiology, Murcia Regional Health Council, Murcia and CIBER Epidemiología y Salud Pública (CIBERESP), Spain
  • ,
  • Aurelio Barrricarte

      Affiliations

    • Public Health Institute of Navarra, Pamplona and CIBER Epidemiología y Salud Pública (CIBERESP), Spain
    • Denotes EPIC's Principal Investigator.
  • ,
  • Francesc Francés

      Affiliations

    • Genetic and Molecular Epidemiology Unit, Department of Preventive Medicine, University of Valencia, Valencia and CIBER Fisiopatología de la Obesidad y Nutrición, ISCIII, Spain
  • ,
  • José María Huerta

      Affiliations

    • Department of Epidemiology, Murcia Regional Health Council, Murcia and CIBER Epidemiología y Salud Pública (CIBERESP), Spain
  • ,
  • Nerea Larrañaga

      Affiliations

    • Public Health Department of Gipuzkoa, Basque Government, San Sebastian, CIBER Epidemiología y Salud Pública (CIBERESP), Spain
  • ,
  • Carmen Martínez

      Affiliations

    • Andalusian School of Public Health, Granada y CIBER Epidemiología y Salud Pública CIBERESP, Spain
    • Denotes EPIC's Principal Investigator.
  • ,
  • Pablo Martinez-Camblor

      Affiliations

    • Public Health Department of Gipuzkoa, Basque Government, San Sebastian, CIBER Epidemiología y Salud Pública (CIBERESP), Spain
  • ,
  • Esther Molina

      Affiliations

    • Andalusian School of Public Health, Granada y CIBER Epidemiología y Salud Pública CIBERESP, Spain
  • ,
  • Carmen Navarro

      Affiliations

    • Department of Epidemiology, Murcia Regional Health Council, Murcia and CIBER Epidemiología y Salud Pública (CIBERESP), Spain
    • Denotes EPIC's Principal Investigator.
  • ,
  • Jose R. Quirós

      Affiliations

    • Public Health and Health Planning Directorate, Asturias, Spain
    • Denotes EPIC's Principal Investigator.
  • ,
  • Laudina Rodríguez

      Affiliations

    • Public Health and Health Planning Directorate, Asturias, Spain
  • ,
  • María José Sánchez

      Affiliations

    • Andalusian School of Public Health, Granada y CIBER Epidemiología y Salud Pública CIBERESP, Spain
  • ,
  • Emilio Ros

      Affiliations

    • Lipid Clinic, Endocrinology and Nutrition Service, IDIBAPS, Hospital Clínic, Barcelona and CIBER Fisiopatología de la Obesidad y Nutrición, ISCIII, Spain
  • ,
  • Nuria Sala

      Affiliations

    • Unit of Nutrition, Environment and Cancer, Cancer Epidemiology Research Programme, Catalan Institute of Oncology (ICO), Barcelona, Spain
  • ,
  • Carlos A. González

      Affiliations

    • Unit of Nutrition, Environment and Cancer, Cancer Epidemiology Research Programme, Catalan Institute of Oncology (ICO), Barcelona, Spain
    • Denotes EPIC's Principal Investigator.
    • These senior authors contributed equally to this work.
  • ,
  • Concepción Moreno-Iribas

      Affiliations

    • Public Health Institute of Navarra, Pamplona and CIBER Epidemiología y Salud Pública (CIBERESP), Spain
    • Departments of Pediatrics, Obstetrics and Gynecology, and Preventive Medicine, Universidad Autónoma de Barcelona, Barcelona
    • These senior authors contributed equally to this work.

Received 30 December 2009; accepted 1 April 2010. published online 06 August 2010.

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 This study was funded by a research grant (FIS) of the Spanish Ministry of Health (PI041224; PI042342; PI041822; PI042188); RETIC (RD06/0020 and RD07/0067/0006); CIBER OBN 06/03; CIBERESP and the Spanish Regional Governments of Andalusia, Asturias, Basque Country, Murcia and Navarra and the Catalan Institute of Oncology.

☆☆ None of the funding sources played a role in the design, collection, analysis or interpretation of the data or in the decision to submit the manuscript for publication. None of the authors has declared any potential conflict of interest.

PII: S0955-2863(10)00101-4

doi:10.1016/j.jnutbio.2010.04.003

The Journal of Nutritional Biochemistry
Volume 22, Issue 5 , Pages 487-494, May 2011