The Journal of Nutritional Biochemistry
Volume 21, Issue 12 , Pages 1232-1237 , December 2010

Molecular mechanisms involved in the enhancement of mitochondrial malate dehydrogenase activity by calcitriol in chick intestine

Received 29 June 2009 ,Revised 14 October 2009 ,Accepted 27 October 2009.

References 

  1. Pérez A, Picotto G, Carpentieri A, Rivoira M, Peralta M, Tolosa de Talamoni N. Minireview on regulation of intestinal calcium absorption. Emphasis on molecular mechanisms of transcellular pathway. Digestion. 2008;77:22–34
  2. Tolosa de Talamoni N. Calcium and phosphorous deficiencies alter the lipid composition and fluidity of intestinal basolateral membranes. Comp Biochem Physiol A Physiol. 1996;115:309–315
  3. Centeno V, Díaz de Barboza G, Marchionatti A, Alisio A, Dallorso M, Nasif R, et al. Dietary calcium deficiency increases Ca2+ uptake and Ca2+ extrusion mechanisms in chick enterocytes. Comp Biochem Physiol A Mol Integr Physiol. 2004;139:133–141
  4. Wasserman R. Vitamin D and the dual processes of intestinal calcium absorption. J Nutr. 2004;134:3137–3139
  5. Fujita H, Sugimoto K, Inatomi S, Maeda T, Osanai M, Uchiyama Y, et al. Tight junction proteins claudin-2 and -12 are critical for vitamin D-dependent Ca2+ absorption between enterocytes. Mol Biol Cell. 2008;19:1912–1921
  6. Tudpor K, Teerapornpuntakit J, Jantarajit W, Krishnamra N, Charoenphandhu N. 1,25-Dihydroxyvitamin D(3) rapidly stimulates the solvent drag-induced paracellular calcium transport in the duodenum of female rats. J Physiol Sci. 2008;58:297–307
  7. Khanal R, Nemere I. Regulation of intestinal calcium transport. Annu Rev Nutr. 2008;28:179–196
  8. Pérez A, Díaz de Barboza G, Pereira R, Tolosa de Talamoni N. Vitamin D affects Krebs cycle NAD-linked oxidoreductases from chick intestinal mucosa. Biochem Mol Biol Int. 1995;36:537–544
  9. Kelly D, Gordon J, Alpers R, Strauss A. The tissue-specific expression and developmental regulation of two nuclear genes encoding rat mitochondrial proteins. Medium chain acyl-CoA dehydrogenase and mitochondrial malate dehydrogenase. J Biol Chem. 1989;264:18921–18925
  10. Alisio A, Cañas F, de Bronia D, Pereira R, Tolosa de Talamoni N. Effect of vitamin D deficiency on lipid composition and calcium transport in basolateral membrane vesicles from chick intestine. Biochem Mol Biol Int. 1997;42:339–347
  11. Tolosa de Talamoni N, Mykkanen H, Wasserman R. Enhancement of sulfhydryl group availability in the intestinal brush border membrane by deficiencies of dietary calcium and phosphorus in chicks. J Nutr. 1990;120:1198–1204
  12. Tolosa de Talamoni N, Pereira R, de Bronia D, Moreno J, Cañas F. Phospholipids and sialic acid changes produced by vitamin D3 on intestinal mitochondria. Metabolism. 1985;34:1007–1011
  13. Gornall A, Bardawill C, David M. Determination of serum proteins by means of the Biuret reaction. J Biol Chem. 1949;177:751–766
  14. Laemmli U. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 1970;227:680–685
  15. Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A. 1979;76:4350–4354
  16. Serafim T, Matos J, Sardao V, Pereira G, Branco A, Pereira S, et al. Sanguinarine cytotoxicity on mouse melanoma K1735-M2 cells—nuclear vs. mitochondrial effects. Biochemical Pharmacol. 2008;76:1459–1475
  17. Liang C, Barnes J, Balakir R, Sacktor B. Characterization of 1,25(OH)2D3-dependent calcium uptake in isolated chick duodenal cells. J Membr Biol. 1986;90:145–156
  18. Tolosa de Talamoni N, Mykkanen H, Cai Q, Wasserman R. Hormonal effects on the sulfhydryl groups associated with intestinal brush border membrane proteins. Biochim Biophys Acta. 1991;1094:224–230
  19. Wong K, Szeto F, Zhang W, Ye H, Kong J, Zhang Z, et al. Involvement of the vitamin D receptor in energy metabolism: regulation of uncoupling proteins. Am J Physiol Endocrinol Metab. 2009;296:E820–E828
  20. Billaudel B, Barakat L, Faure-Dussert A. Vitamin D3 deficiency and alterations of glucose metabolism in rat endocrine pancreas. Diabetes Metab. 1998;23:344–350
  21. Stio M, Iantomasi T, Favilli F, Marraccini P, Lunghi B, Vincenzini M, et al. Glutathione metabolism in heart and liver of the aging rat. Biochem Cell Biol. 1994;72:58–61
  22. Stio M, Lunghi B, Celli A, Treves C. Vitamin D-related modification of enzyme activities in synaptosomes and mitochondria isolated from rat cerebral cortex.. Biochem Mol Biol Int. 1995;37:813–820
  23. McCormack J, Halestrap A, Denton R. Role of calcium ions in regulation of mammalian intramitochondrial metabolism. Physiol Rev. 1990;70:391–425
  24. Denton R. Regulation of mitochondrial dehydrogenases by calcium ions. Biochim Biophys Acta. 2009;1787:1309–1316
  25. Khanal R, Peters T, Smith N, Nemere I. Membrane receptor-initiated signaling in 1,25(OH)2D3-stimulated calcium uptake in intestinal epithelial cells. J Cell Biochem. 2008;105:1109–1116
  26. Cohen-Lahav M, Douvdevani A, Chaimovitz C, Shany S. The anti-inflammatory activity of 1,25-dihydroxyvitamin D3 in macrophages. J Steroid Biochem Mol Biol. 2007;103:558–562
  27. Yao J, Bai S, Karnauskas A, Bushinsky D, Favus M. Regulation of renal calcium receptor gene expression by 1,25-dihydroxyvitamin D3 in genetic hypercalciuric stone-forming rats. J Am Soc Nephrol. 2005;16:1300–1309
  28. Fan J, Liu S, Du Y, Morrison J, Shipman R, Pang K. Up-regulation of transporters and enzymes by the vitamin D receptor ligands, 1α,25-dihydroxyvitamin D3 and vitamin D analogs, in the Caco-2 cells monolayer. J Pharmacol Exp Ther. 2009;330:389–402
  29. Zemel M, Sun X. Calcitriol and energy metabolism. Nutr Rev. 2008;66:S139–146
  30. Chatterjee M. Vitamin D and genomic stability. Mutat Res. 2001;475:69–87
  31. Hodges C, Wiggins J, Harrison J. Investigation of the relation of the pH-dependent dissociation of malate dehydrogenase to modification of the enzyme by N-ethylmaleimide. J Biol Chem. 1977;252:6038–6041
  32. Marchionatti A, Perez A, Diaz de Barboza G, Pereira B, Tolosa de Talamoni N. Mitochondrial dysfunction is responsible for the intestinal calcium absorption inhibition induced by menadione. Biochim Biophys Acta. 2008;1780:101–107
  33. Shi H, Norman A, Okamura W, Sen A, Zemel M. 1alpha,25-Dihydroxyvitamin D3 inhibits uncoupling protein 2 expression in human adipocytes. FASEB J. 2002;16:1808–1810
  34. Nasr L, Monet J, Lucas P, Bader C. Vitamin D3 and glucose-6-phosphate dehydrogenase in rat duodenal epithelial cells. Am J Physiol. 1989;257:G760–765
  35. Bao H, Zhao C, Zhang L, Li J, Wu C. Single-nucleotide polymorphisms of mitochondrially coded subunit genes of cytochrome c oxidase in five chicken breeds. Mitochondrial DNA. 2008;19:461–464

 This work was supported by grants from FONCYT (PICT 2005- 32464), CONICET (PIP 2005-06 / 5394) and SECYT (UNC), Argentina. Prof. Dr. Nori Tolosa de Talamoni is a member of Investigator Career from the Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET). Dr. Viviana Centeno is a postdoctoral fellow from Secretaria de Ciencia y Técnica, Universidad Nacional de Córdoba (SECYT-UNC).

PII: S0955-2863(09)00232-0

doi: 10.1016/j.jnutbio.2009.10.011

The Journal of Nutritional Biochemistry
Volume 21, Issue 12 , Pages 1232-1237 , December 2010