The Journal of Nutritional Biochemistry
Volume 21, Issue 12 , Pages 1222-1231, December 2010

α-Tocopherol is an effective Phase II enzyme inducer: protective effects on acrolein-induced oxidative stress and mitochondrial dysfunction in human retinal pigment epithelial cells☆

  • Zhihui Feng

      Affiliations

    • Institute for Nutritional Science, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
    • Graduate School of the Chinese Academy of Sciences, Beijing 100081, China
    • ,
  • Zhongbo Liu

      Affiliations

    • Institute for Nutritional Science, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
    • Graduate School of the Chinese Academy of Sciences, Beijing 100081, China
    • ,
  • Xuesen Li

      Affiliations

    • Institute for Nutritional Science, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
    • Graduate School of the Chinese Academy of Sciences, Beijing 100081, China
    • ,
  • Haiqun Jia

      Affiliations

    • Institute for Nutritional Science, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
    • Graduate School of the Chinese Academy of Sciences, Beijing 100081, China
    • ,
  • Lijuan Sun

      Affiliations

    • College of Physical Education and Health, East China Normal University, Shanghai 200241, China
    • ,
  • Chuan Tian

      Affiliations

    • Institute for Nutritional Science, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
    • Graduate School of the Chinese Academy of Sciences, Beijing 100081, China
    • ,
  • Lihong Jia

      Affiliations

    • Department of Nutrition and Food Hygiene, School of Public Health, China Medical University, Shenyang 110001, China
    • ,
  • Jiankang Liu

      Affiliations

    • Institute of Mitochondrial Biology and Medicine, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, Xi'an Jiaotong University School of Life Science and Technology, Xi'an 710049, China
    • Corresponding Author InformationCorresponding author. Institute of Mitochondrial Biology and Medicine, Xi'an Jiaotong University School of Life Science and Technology, Xi'an 710049, China. Tel.: +85 29 8266 4232.

Received 11 April 2009; received in revised form 15 September 2009; accepted 30 October 2009. published online 15 February 2010.

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☆ This study was supported by the National Eye Institute, NIH grant EY0160101, Macular Degeneration Research (MDR Grant 2005-038), Chinese Academy of Sciences grant 05PG14104 and a starting fund of 985 Plan of Xi'an Jiaotong University.

PII: S0955-2863(09)00231-9

doi:10.1016/j.jnutbio.2009.10.010

The Journal of Nutritional Biochemistry
Volume 21, Issue 12 , Pages 1222-1231, December 2010

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