The Journal of Nutritional Biochemistry
Volume 20, Issue 12 , Pages 917-926 , December 2009

DNA methylation, an epigenetic mechanism connecting folate to healthy embryonic development and aging

  • Kyong-chol Kim

      Affiliations

    • Vitamins and Carcinogenesis Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    • Department of Family Medicine, Mizmedi Hospital, 135-280 Seoul, South Korea
  • ,
  • Simonetta Friso

      Affiliations

    • Department of Clinical and Experimental Medicine, University of Verona School of Medicine, 37134 Verona, Italy
  • ,
  • Sang-Woon Choi, MD, PhD

      Affiliations

    • Vitamins and Carcinogenesis Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 617 556 3007.

Received 30 December 2008 ,Revised 19 April 2009 ,Accepted 22 June 2009.

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 This material is based upon the work supported by the US Department of Agriculture, under agreement no. 581950-9-001. Any opinions, findings, conclusion or recommendations expressed in this publication are those of the author(s) and do not necessarily reflect the view of the US Department of Agriculture. Authors do not have any competing interest. This project has been supported in part by the National Institute of Health grants R21 AA016681 and R01 AG025834 (SWC).

PII: S0955-2863(09)00134-X

doi: 10.1016/j.jnutbio.2009.06.008

The Journal of Nutritional Biochemistry
Volume 20, Issue 12 , Pages 917-926 , December 2009