The Journal of Nutritional Biochemistry
Volume 21, Issue 9 , Pages 818-826, September 2010

4-Hydroxynonenal, a lipid peroxidation product of dietary polyunsaturated fatty acids, has anticarcinogenic properties in colon carcinoma cell lines through the inhibition of telomerase activity☆

  • Stefania Pizzimenti

      Affiliations

    • Department of Medicine and Experimental Oncology, Section of General Pathology, University of Turin, 10125 Torino, Italy
    • Corresponding Author InformationCorresponding author. Dipartimento di Medicina ed Oncologia Sperimentale, Sezione di Patologia Generale, 10153 Torino, Italy. Tel.: +39 011 6707763; fax: +39 011 6707753.
    • S.P. and E.M. have contributed equally to the studies present in this manuscript.
    • ,
  • Elisa Menegatti

      Affiliations

    • Department of Experimental Medicine and Oncology, Section of Clinical Pathology, University of Turin, 10125 Torino, Italy
    • S.P. and E.M. have contributed equally to the studies present in this manuscript.
    • ,
  • Daniela Berardi

      Affiliations

    • Department of Experimental Medicine and Oncology, Section of Clinical Pathology, University of Turin, 10125 Torino, Italy
    • ,
  • Cristina Toaldo

      Affiliations

    • Department of Medicine and Experimental Oncology, Section of General Pathology, University of Turin, 10125 Torino, Italy
    • ,
  • Piergiorgio Pettazzoni

      Affiliations

    • Department of Medicine and Experimental Oncology, Section of General Pathology, University of Turin, 10125 Torino, Italy
    • ,
  • Rosalba Minelli

      Affiliations

    • Department of Medicine and Experimental Oncology, Section of General Pathology, University of Turin, 10125 Torino, Italy
    • ,
  • Barbara Giglioni

      Affiliations

    • Institute of Molecular Bioimaging and Physiology (IBFM), National Research Council (CNR), 20090 Segrate (Milano), Italy
    • ,
  • Angelo Cerbone

      Affiliations

    • Department of Medicine and Experimental Oncology, Section of General Pathology, University of Turin, 10125 Torino, Italy
    • ,
  • Mario U. Dianzani

      Affiliations

    • Department of Medicine and Experimental Oncology, Section of General Pathology, University of Turin, 10125 Torino, Italy
    • ,
  • Carlo Ferretti

      Affiliations

    • Department of Anatomy, Pharmacology and Forensic Medicine, University of Turin, 10125 Torino, Italy.
    • ,
  • Giuseppina Barrera

      Affiliations

    • Department of Medicine and Experimental Oncology, Section of General Pathology, University of Turin, 10125 Torino, Italy

Received 20 March 2009; received in revised form 8 June 2009; accepted 15 June 2009. published online 04 September 2009.

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☆ Supported by grants from Compagnia di San Paolo and University of Turin (ex 60%) funds (G.B.).

PII: S0955-2863(09)00131-4

doi:10.1016/j.jnutbio.2009.06.005

The Journal of Nutritional Biochemistry
Volume 21, Issue 9 , Pages 818-826, September 2010

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