The Journal of Nutritional Biochemistry
Volume 21, Issue 8 , Pages 717-725, August 2010

Anti-inflammatory properties of a pomegranate extract and its metabolite urolithin-A in a colitis rat model and the effect of colon inflammation on phenolic metabolism☆

  • Mar Larrosa

      Affiliations

    • Department of Preclinical and Clinical Pharmacology, University of Florence, I-50139 Florence, Italy
    • ,
  • Antonio González-Sarrías

      Affiliations

    • Research Group on Quality, Safety and Bioactivity of Plant Foods, Department of Food Science and Technology, CEBAS-CSIC, 30100 Campus de Espinardo, Murcia, Spain
    • ,
  • María J. Yáñez-Gascón

      Affiliations

    • Research Group on Quality, Safety and Bioactivity of Plant Foods, Department of Food Science and Technology, CEBAS-CSIC, 30100 Campus de Espinardo, Murcia, Spain
    • ,
  • María V. Selma

      Affiliations

    • Research Group on Quality, Safety and Bioactivity of Plant Foods, Department of Food Science and Technology, CEBAS-CSIC, 30100 Campus de Espinardo, Murcia, Spain
    • ,
  • María Azorín-Ortuño

      Affiliations

    • Research Group on Quality, Safety and Bioactivity of Plant Foods, Department of Food Science and Technology, CEBAS-CSIC, 30100 Campus de Espinardo, Murcia, Spain
    • ,
  • Simona Toti

      Affiliations

    • Department of Preclinical and Clinical Pharmacology, University of Florence, I-50139 Florence, Italy
    • ,
  • Francisco Tomás-Barberán

      Affiliations

    • Research Group on Quality, Safety and Bioactivity of Plant Foods, Department of Food Science and Technology, CEBAS-CSIC, 30100 Campus de Espinardo, Murcia, Spain
    • ,
  • Piero Dolara

      Affiliations

    • Department of Preclinical and Clinical Pharmacology, University of Florence, I-50139 Florence, Italy
    • ,
  • Juan Carlos Espín

      Affiliations

    • Department of Preclinical and Clinical Pharmacology, University of Florence, I-50139 Florence, Italy
    • Corresponding Author InformationCorresponding author. Department of Food Science and Technology, CEBAS-CSIC, 30100 Campus de Espinardo, Murcia, Spain. Tel.: +34 968 396344; fax: +34 968 396213.

Received 24 February 2009; received in revised form 18 April 2009; accepted 23 April 2009. published online 21 July 2009.

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☆ This work has been supported by the Projects CICYT-BFU2007-60576 and Consolider Ingenio 2010, CSD2007-00063 (Fun-C-Food). M.L. is holder of a postdoctoral grant from MCINN (Spain), M.V.S. is the holder of a I3P-postdoctoral grant from CSIC (Spain), A.G.S. is holder of a FPI predoctoral grant from MICINN and M.A.O. is the holder of a JAE-predoctoral grant from CSIC.

PII: S0955-2863(09)00099-0

doi:10.1016/j.jnutbio.2009.04.012

The Journal of Nutritional Biochemistry
Volume 21, Issue 8 , Pages 717-725, August 2010

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