« Previous
Next »
The Journal of Nutritional Biochemistry
Volume 21, Issue 7
, Pages 580-588
, July 2010
l-Carnitine attenuates angiotensin II-induced proliferation of cardiac fibroblasts: role of NADPH oxidase inhibition and decreased sphingosine-1-phosphate generation
References
- . Kinetics, pharmacokinetics, and regulation of l-carnitine and acetyl-l-carnitine metabolism. Ann N Y Acad Sci. 2004;1033:30–41
- . Antimony-induced cardiomyopathy in guinea-pig and protection by l-carnitine. Br J Pharmacol. 2005;144:17–27
- L -propionyl-carnitine as superoxide scavenger, antioxidant, and DNA cleavage protector. Cell Biol Toxicol. 2000;16:99–104
- Effects of l-carnitine administration on left ventricular remodeling after acute anterior myocardial infarction: the l-Carnitine Ecocardiografia Digitalizzata Infarto Miocardico (CEDIM) Trial. J Am Coll Cardiol. 1995;26:380–387
- . Angiotensin II, adhesion, and cardiac fibrosis. Cardiovasc Res. 2000;46:264–268
- Role of NADH/NADPH oxidase-derived H2O2 in angiotensin II-induced vascular hypertrophy. Hypertension. 1998;32:488–495
- . Involvement of reactive oxygen species in angiotensin II-induced endothelin-1 gene expression in rat cardiac fibroblasts. J Am Coll Cardiol. 2003;42:1845–1854
- . Sphingosine 1-phosphate signalling in mammalian cells. Biochem J. 2000;349:385–402
- . Point-counterpoint of sphingosine 1-phosphate metabolism. Circ Res. 2004;94:724–734
- Agonists of peroxisome-proliferator activated receptor-gamma reduce renal ischemia/reperfusion injury. Am J Nephrol. 2003;23:267–276
- Acid sphingomyelinase and its redox amplification in formation of lipid raft redox signaling platforms in endothelial cells. Antioxid Redox Signal. 2007;9:817–828
- . Sphingosine kinase-dependent activation of endothelial nitric oxide synthase by angiotensin II. Arterioscler Thromb Vasc Biol. 2006;26:2043–2048
- The CYP4A isoforms hydroxylate epoxyeicosatrienoic acids to form high affinity peroxisome proliferator-activated receptor ligands. J Biol Chem. 2002;277:35105–35112
- . Human endothelial nitric oxide synthase gene delivery protects against cardiac remodeling and reduces oxidative stress after myocardial infarction. Life Sci. 2005;76:2457–2471
- MRI visualized neo-intimal dissection and co-localization of novel apoptotic markers apolipoprotein C-1, ceramide and caspase-3 in a Watanabe hyperlipidemic rabbit model. Atherosclerosis. 2007;191:82–89
- . Effects of short- and long-term feeding of l-carnitine and congeners on the production of eicosanoids from rat peritoneal leucocytes. Br J Nutr. 1994;72:785–793
- . l-carnitine and propionyl-l-carnitine improve endothelial dysfunction in spontaneously hypertensive rats: different participation of NO and COX-products. Life Sci. 2005;77:2082–2097
- . Propionyl-l-carnitine dilates human subcutaneous arteries through an endothelium-dependent mechanism. J Vasc Surg. 1999;29:1097–1103
- . A simple, rapid and sensitive fluorimetric assay for the measurement of cell-mediated cytotoxicity. J Immunol Methods. 1995;185:199–208
- Reactive oxygen species mediate cyclic strain-induced endothelin-1 gene expression via Ras/Raf/extracellular signal-regulated kinase pathway in endothelial cells. J Mol Cell Cardiol. 2001;33:1805–1814
- . Reactive oxygen species modulate endothelin-I-induced c-fos gene expression in cardiomyocytes. Cardiovasc Res. 1999;41:654–662
- . Lucigenin chemiluminescence in the assessment of neutrophil superoxide production. J Immunol Methods. 1987;97:209–213
- . Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res. 1994;74:1141–1148
- . Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation. J Immunol. 1983;130:1910–1917
- . Enzymatic method for measurement of sphingosine 1-phosphate. Methods Enzymol. 2000;312:9–16
- . Fibroblast growth factor and heparin protect endothelial cells from the effects of interleukin 1. J Cell Physiol. 1996;167:229–237
- . Mechanism of cardiac fibrosis by angiotensin. New insight revealed by genetic engineering. Trends Cardiovasc Med. 1999;9:180–184
- . TGF-beta1 and angiotensin networking in cardiac remodeling. Cardiovasc Res. 2004;63:423–432
- . Redox regulation of angiotensin II signaling in the heart. J Cell Mol Med. 2004;8:144–152
- Sphingolipids–the enigmatic lipid class: biochemistry, physiology, and pathophysiology. Toxicol Appl Pharmacol. 1997;142:208–225
- . l-carnitine prevents doxorubicin-induced apoptosis of cardiac myocytes: role of inhibition of ceramide generation. FASEB J. 1999;13:1501–1510
- . The sphingolipid salvage pathway in ceramide metabolism and signaling. Cell Signal. 2008;20:1010–1018
- The role of ANG II and endothelin-1 in exercise-induced diastolic dysfunction in heart failure. Am J Physiol Heart Circ Physiol. 2001;280:H1853–H1860
- . Peroxisome proliferator-activated receptors as transcriptional nodal points and therapeutic targets. Circulation. 2007;115:518–533
- PPARalpha activator effects on Ang II-induced vascular oxidative stress and inflammation. Hypertension. 2002;40:866–871
- . Identification of a functional peroxisome proliferator-activated receptor response element in the rat catalase promoter. Mol Endocrinol. 2002;16:2793–2801
- . PPARalpha agonist induces the accumulation of ceramide in the heart of rats fed high-fat diet. J Physiol Pharmacol. 2007;58:57–72
☆ Funding: This work was supported by the China Medical University (CMU-97-212), Taichung, and Shin Kong Wu Ho-Su Memorial Hospital (SKH-TMU-97-03), Taipei, Taiwan, R.O.C.
PII: S0955-2863(09)00060-6
doi: 10.1016/j.jnutbio.2009.03.003
© 2010 Elsevier Inc. All rights reserved.
« Previous
Next »
The Journal of Nutritional Biochemistry
Volume 21, Issue 7
, Pages 580-588
, July 2010
