« Previous
Next »
The Journal of Nutritional Biochemistry
Volume 21, Issue 4
, Pages 325-331
, April 2010
Presence of low-grade inflammation impaired postprandial stimulation of muscle protein synthesis in old rats
References
- . Protein and functional consequences of deficiency. In: Horwitz A, MacFayden DM, Munro HN, Scrimshaw NS, Steen B, Williams TF editor. Nutrition in the elderly. New York: Oxford University; 1989;p. 65–84
- Altered response of protein synthesis to nutritional state and endurance training in old rats. Am J Physiol. 1995;268:E328–E335
- . Postprandial stimulation of muscle protein synthesis in old rats can be restored by a leucine-supplemented meal. J Nutr. 2002;132:95–100
- Pulse protein feeding pattern restores stimulation of muscle protein synthesis during the feeding period in old rats. J Nutr. 2002;132:1002–1008
- A leucine-supplemented diet restores the defective postprandial inhibition of proteasome-dependent proteolysis in aged rat skeletal muscle. J Physiol. 2005;569:489–499
- Impaired anabolic response of muscle protein synthesis is associated with S6K1 dysregulation in elderly humans. FASEB J. 2004;18:1586–1587
- Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle. FASEB J. 2005;19:422–424
- Leucine supplementation improves muscle protein synthesis in elderly men independently of hyperaminoacidaemia. J Physiol. 2006;575:305–315
- . Sustained modifications of protein metabolism in various tissues in a rat model of long-lasting sepsis. Clin Sci. 1998;94:413–423
- . Acute-phase proteins and other systemic responses to inflammation. N Engl J Med. 1999;340:448–454
- . A sustained rat model for studying long-lasting catabolic state of sepsis. Infect Immun. 1999;67:1079–1085
- . TNF-alpha impairs heart and skeletal muscle protein synthesis by altering translation initiation. Am J Physiol Endocrinol Metab. 2002;282:E336–E347
- . Control of protein synthesis by amino acid availability. Curr Opin Clin Nutr Metab Care. 2002;5:63–67
- . Stimulation of in vitro rat muscle protein synthesis by leucine decreases with age. J Nutr. 2000;130:2630–2635
- Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly. Am J Med. 1999;106:506–512
- Change in muscle strength explains accelerated decline of physical function in older women with high interleukin-6 serum levels. J Am Geriatr Soc. 2002;50:1947–1954
- . Coagulation and activation of inflammatory pathways in the development of functional decline and mortality in the elderly. Am J Med. 2003;114:180–187
- . Circulating acute phase mediators and skeletal muscle performance in hospitalized geriatric patients. J Gerontol A Biol Sci Med Sci. 2005;60:361–367
- . Inflammatory markers and loss of muscle mass (sarcopenia) and strength. Am J Med. 2006;119:U82–U90
- Relationship of interleukin-6 and tumor necrosis factor-alpha with muscle mass and muscle strength in elderly men and women: the health ABC study. J Gerontol A Biol Sci Med Sci. 2002;57:M326–M332
- Acute phase protein levels and thymus, spleen and plasma protein synthesis rates differ in adult and old rats. J Nutr. 2003;133:215–219
- . Age-related differences in skeletal muscle protein synthesis: relation to markers of immune activation. Am J Physiol Endocrinol Metab. 2005;288:E883–E891
- Prognostic values of alpha2-macroglobulin, fibrinogen and albumin in regards to mortality and frailty in old rats. Exp Gerontol. 2007;42:498–505
- . Optimized microturbidimetric assay for fibrinogen. Clin Chem. 1989;35:211–214
- . The response of liver albumin synthesis to infection in rats varies with the phase of the inflammatory process. Clin Sci. 2002;102:107–114
- . Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty. Annu Rev Med. 2000;51:245–270
- . Association of fibrinogen, C-reactive protein, albumin, or leukocyte count with coronary heart disease: meta-analyses of prospective studies. JAMA. 1998;279:1477–1482
- Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses. Br Med J. 2000;321:199–204
- . Altered regulation of IL-6 production with normal aging. Possible linkage to the age-associated decline in dehydroepiandrosterone and its sulfated derivative. J Immunol. 1993;150:5219–5230
- . Chronic inflammation alters protein metabolism in several organs of adult rats. J Nutr. 2002;132:1921–1928
- . Insulin-like growth factor-1 and insulin resistance in skeletal muscles of adult and old rats. Endocrinology. 1994;134:1475–1484
- . Basal muscle amino acid kinetics and protein synthesis in healthy young and older men. JAMA. 2001;286:1206–1212
- Protein pulse feeding improves protein retention in elderly women. Am J Clin Nutr. 1999;69:1202–1208
- . Meal feeding alters translational control of gene expression in rat liver. J Nutr. 2005;135:367–375
- . Pentoxifylline decreases the body weight loss and muscle protein wasting characteristics of sepsis. Am J Physiol. 1993;265:E660–E666
- Cytokine modulation by PX differently affects specific acute phase proteins during sepsis in rats. Am J Physiol. 1998;275:R1412–R1419
- . Proinflammatory cytokines and skeletal muscle. Curr Opin Clin Nutr Metab Care. 2004;7:265–269
- Metabolic response to injury and sepsis: changes in protein metabolism. Nutrition. 1997;13:S52–S57
- . The amino acid requirements of disease. Clin Nutr. 2001;(Suppl 1):15–22
☆ This project was supported by a grant from the French Ministry of Research (UNH1019).
PII: S0955-2863(09)00013-8
doi: 10.1016/j.jnutbio.2009.01.005
© 2010 Elsevier Inc. All rights reserved.
« Previous
Next »
The Journal of Nutritional Biochemistry
Volume 21, Issue 4
, Pages 325-331
, April 2010
