The Journal of Nutritional Biochemistry
Volume 21, Issue 3 , Pages 247-254, March 2010

Caseinphosphopeptide-induced calcium uptake in human intestinal cell lines HT-29 and Caco2 is correlated to cellular differentiation

  • Stefania Cosentino

      Affiliations

    • Department of Medical Chemistry, Biochemistry and Biotechnology, LITA Segrate, University of Milan, 20090, Milan, Italy
    • These authors contributed equally to the study.
  • ,
  • Claudia Gravaghi

      Affiliations

    • Department of Medical Chemistry, Biochemistry and Biotechnology, LITA Segrate, University of Milan, 20090, Milan, Italy
    • Strang Cancer Research Laboratory, Division of Gastroenterology and Hepatology, Department of Medicine, Weill Medical College of Cornell University, New York, NY 10065, USA
    • These authors contributed equally to the study.
  • ,
  • Elena Donetti

      Affiliations

    • DMU, Department of Human Morphology, University of Milan, 20133 Milan, Italy
  • ,
  • Bianca M. Donida

      Affiliations

    • Department of Medical Chemistry, Biochemistry and Biotechnology, LITA Segrate, University of Milan, 20090, Milan, Italy
  • ,
  • Giovanni Lombardi

      Affiliations

    • IRCCS Istituto Ortopedico Galeazzi, 20133 Milan, Italy
  • ,
  • Marzia Bedoni

      Affiliations

    • DMU, Department of Human Morphology, University of Milan, 20133 Milan, Italy
    • Fondazione Don Gnocchi ONLUS, Polo Tecnologico 20148 Milan, Italy
  • ,
  • Amelia Fiorilli

      Affiliations

    • Department of Medical Chemistry, Biochemistry and Biotechnology, LITA Segrate, University of Milan, 20090, Milan, Italy
  • ,
  • Guido Tettamanti

      Affiliations

    • Department of Medical Chemistry, Biochemistry and Biotechnology, LITA Segrate, University of Milan, 20090, Milan, Italy
  • ,
  • Anita Ferraretto

      Affiliations

    • Department of Medical Chemistry, Biochemistry and Biotechnology, LITA Segrate, University of Milan, 20090, Milan, Italy
    • Corresponding Author InformationCorresponding author. Tel: +39 0250330341; fax: +39 0250230365.

Received 29 July 2008; received in revised form 16 November 2008; accepted 15 December 2008. published online 15 April 2009.

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 This work was supported in part by the EU FAIR Programme Project CT98-3077 (“Caseinphosphopeptide (CPP): Nutraceutical/functional food ingredients for food and pharmaceutical applications”) and by Fondazione Romeo and Enrica Invernizzi (“CPP: role in the calcium intestinal absorption and its utilization. A perspective study on their possible usage as nutraceuticals or functional food to favour calcium bioavailability”).

PII: S0955-2863(09)00002-3

doi:10.1016/j.jnutbio.2008.12.016

The Journal of Nutritional Biochemistry
Volume 21, Issue 3 , Pages 247-254, March 2010