The Journal of Nutritional Biochemistry
Volume 20, Issue 3 , Pages 202-209 , March 2009

Role of caveolin-1 in EGCG-mediated protection against linoleic-acid-induced endothelial cell activation

  • Yuanyuan Zheng

      Affiliations

    • Graduate Center for Nutritional Sciences, University of Kentucky, Lexington, KY 40536-0200, USA
    • ,
  • Eum Jin Lim

      Affiliations

    • Molecular and Cell Nutrition Laboratory, College of Agriculture, University of Kentucky, Lexington, KY 40536-0200, USA
    • ,
  • Lei Wang

      Affiliations

    • Graduate Center for Nutritional Sciences, University of Kentucky, Lexington, KY 40536-0200, USA
    • ,
  • Eric J. Smart

      Affiliations

    • Graduate Center for Nutritional Sciences, University of Kentucky, Lexington, KY 40536-0200, USA
    • Department of Pediatrics, University of Kentucky, Lexington, KY 40536-0200,USA
    • ,
  • Michal Toborek

      Affiliations

    • Graduate Center for Nutritional Sciences, University of Kentucky, Lexington, KY 40536-0200, USA
    • Department of Neurosurgery, University of Kentucky, Lexington, KY 40536-0200, USA
    • ,
  • Bernhard Hennig

      Affiliations

    • Graduate Center for Nutritional Sciences, University of Kentucky, Lexington, KY 40536-0200, USA
    • Molecular and Cell Nutrition Laboratory, College of Agriculture, University of Kentucky, Lexington, KY 40536-0200, USA
    • Corresponding Author InformationCorresponding author. Molecular and Cell Nutrition Laboratory, College of Agriculture, University of Kentucky, Lexington, KY 40536-0200, USA. Tel.: +1 859 253 4933x81343; fax: +1 859 257 1811.

Received 15 October 2007 ,Revised 29 January 2008 ,Accepted 6 February 2008.

References 

  1. Ross R. Atherosclerosis — an inflammatory disease. N Engl J Med. 1999;340:115–126
  2. Sohn HY, Krotz F. Cyclooxygenase inhibition and atherothrombosis. Curr Drug Targets. 2006;7:1275–1284
  3. Cipollone F, Fazia ML. Cyclooxygenase-2 inhibition: vascular inflammation and cardiovascular risk. Curr Atheroscler Rep. 2006;8:245–251
  4. Austin MA, McKnight B, Edwards KL, Bradley CM, McNeely MJ, Psaty BM, et al. Cardiovascular disease mortality in familial forms of hypertriglyceridemia: a 20-year prospective study. Circulation. 2000;101:2777–2782
  5. Malloy MJ, Kane JP. A risk factor for atherosclerosis: triglyceride-rich lipoproteins. Adv Intern Med. 2001;47:111–136
  6. Psota TL, Gebauer SK, Kris-Etherton P. Dietary omega-3 fatty acid intake and cardiovascular risk. Am J Cardiol. 2006;98:3i–18i
  7. Hennig B, Toborek M, McClain CJ. High-energy diets, fatty acids and endothelial cell function: implications for atherosclerosis. J Am Coll Nutr. 2001;20:97–105
  8. Hennig B, Lei W, Arzuaga X, Ghosh DD, Saraswathi V, Toborek M. Linoleic acid induces proinflammatory events in vascular endothelial cells via activation of PI3K/Akt and ERK1/2 signaling. J Nutr Biochem. 2006;17:766–772
  9. Horia E, Watkins BA. Comparison of stearidonic acid and alpha-linolenic acid on PGE2 production and COX-2 protein levels in MDA-MB-231 breast cancer cell cultures. J Nutr Biochem. 2005;16:184–192
  10. Munoz-Espada AC, Watkins BA. Cyanidin attenuates PGE2 production and cyclooxygenase-2 expression in LNCaP human prostate cancer cells. J Nutr Biochem. 2006;17:589–596
  11. Kris-Etherton PM, Lefevre M, Beecher GR, Gross MD, Keen CL, Etherton TD. Bioactive compounds in nutrition and health-research methodologies for establishing biological function: the antioxidant and anti-inflammatory effects of flavonoids on atherosclerosis. Annu Rev Nutr. 2004;24:511–538
  12. Manach C, Scalbert A, Morand C, Remesy C, Jimenez L. Polyphenols: food sources and bioavailability. Am J Clin Nutr. 2004;79:727–747
  13. Frank PG, Woodman SE, Park DS, Lisanti MP. Caveolin, caveolae, and endothelial cell function. Arterioscler Thromb Vasc Biol. 2003;23:1161–1168
  14. Frank PG, Lee H, Park DS, Tandon NN, Scherer PE, Lisanti MP. Genetic ablation of caveolin-1 confers protection against atherosclerosis. Arterioscler Thromb Vasc Biol. 2004;24:98–105
  15. Matveev S, Li X, Everson W, Smart EJ. The role of caveolae and caveolin in vesicle-dependent and vesicle-independent trafficking. Adv Drug Deliv Rev. 2001;49:237–250
  16. Ma DW, Seo J, Davidson LA, Callaway ES, Fan YY, Lupton JR, et al. n-3 PUFA alter caveolae lipid composition and resident protein localization in mouse colon. Faseb J. 2004;18:1040–1042
  17. Cha SH, Jung NH, Kim BR, Kim HW, Kwak JO. Evidence for cyclooxygenase-1 association with caveolin-1 and -2 in cultured human embryonic kidney (HEK 293) cells. IUBMB Life. 2004;56:221–227
  18. Kwak JO, Lee WK, Kim HW, Jung SM, Oh KJ, Jung SY, et al. Evidence for cyclooxygenase-2 association with caveolin-3 in primary cultured rat chondrocytes. J Korean Med Sci. 2006;21:100–106
  19. Sanchez M, Galisteo M, Vera R, Villar IC, Zarzuelo A, Tamargo J, et al. Quercetin downregulates NADPH oxidase, increases eNOS activity and prevents endothelial dysfunction in spontaneously hypertensive rats. J Hypertens. 2006;24:75–84
  20. Tang YB, Wang QL, Zhu BY, Huang HL, Liao DF. Phytoestrogen genistein supplementation increases eNOS and decreases caveolin-1 expression in ovariectomized rat hearts. Sheng Li Xue Bao. 2005;57:373–378
  21. Nabi IR, Le PU. Caveolae/raft-dependent endocytosis. J Cell Biol. 2003;161:673–677
  22. Pignatelli P, Di Santo S, Buchetti B, Sanguigni V, Brunelli A, Violi F. Polyphenols enhance platelet nitric oxide by inhibiting protein kinase C-dependent NADPH oxidase activation: effect on platelet recruitment. Faseb J. 2006;20:1082–1089
  23. Choi YJ, Jeong YJ, Lee YJ, Kwon HM, Kang YH. (−)Epigallocatechin gallate and quercetin enhance survival signaling in response to oxidant-induced human endothelial apoptosis. J Nutr. 2005;135:707–713
  24. Edgell CJ, McDonald CC, Graham JB. Permanent cell line expressing human factor VIII-related antigen established by hybridization. Proc Natl Acad Sci U S A. 1983;80:3734–3737
  25. Toborek M, Lee YW, Kaiser S, Hennig B. Measurement of inflammatory properties of fatty acids in human endothelial cells. Methods Enzymol. 2002;352:198–219
  26. Repetto S, Salani B, Maggi D, Cordera R. Insulin and IGF-I phosphorylate eNOS in HUVECs by a caveolin-1 dependent mechanism. Biochem Biophys Res Commun. 2005;337:849–852
  27. Lim EJ, Kim CW. Functional characterization of the promoter region of the chicken elongation factor-2 gene. Gene. 2007;386:183–190
  28. Sauzeau V, Rolli-Derkinderen M, Marionneau C, Loirand G, Pacaud P. RhoA expression is controlled by nitric oxide through cGMP-dependent protein kinase activation. J Biol Chem. 2003;278:9472–9480
  29. Hennig B, Chung BH, Watkins BA, Alvarado A. Disruption of endothelial barrier function by lipolytic remnants of triglyceride-rich lipoproteins. Atherosclerosis. 1992;95:235–247
  30. Moller DE, Kaufman KD. Metabolic syndrome: a clinical and molecular perspective. Annu Rev Med. 2005;56:45–62
  31. Toborek M, Lee YW, Garrido R, Kaiser S, Hennig B. Unsaturated fatty acids selectively induce an inflammatory environment in human endothelial cells. Am J Clin Nutr. 2002;75:119–125
  32. Yang N, Ying C, Xu M, Zuo X, Ye X, Liu L, et al. High-fat diet up-regulates caveolin-1 expression in aorta of diet-induced obese but not in diet-resistant rats. Cardiovasc Res. 2007;
  33. Jeong YI, Jung ID, Lee JS, Lee CM, Lee JD, Park YM. (−)-Epigallocatechin gallate suppresses indoleamine 2,3-dioxygenase expression in murine dendritic cells: evidences for the COX-2 and STAT1 as potential targets. Biochem Biophys Res Commun. 2007;354:1004–1009
  34. Kundu JK, Na HK, Chun KS, Kim YK, Lee SJ, Lee SS, et al. Inhibition of phorbol ester-induced COX-2 expression by epigallocatechin gallate in mouse skin and cultured human mammary epithelial cells. J Nutr. 2003;133:3805S–3810S
  35. Park JS, Kim MH, Chang HJ, Kim KM, Kim SM, Shin BA, et al. Epigallocatechin-3-gallate inhibits the PDGF-induced VEGF expression in human vascular smooth muscle cells via blocking PDGF receptor and Erk-1/2. Int J Oncol. 2006;29:1247–1252
  36. Adhikari N, Charles N, Lehmann U, Hall JL. Transcription factor and kinase-mediated signaling in atherosclerosis and vascular injury. Curr Atheroscler Rep. 2006;8:252–260
  37. Peng G, Dixon DA, Muga SJ, Smith TJ, Wargovich MJ. Green tea polyphenol (−)-epigallocatechin-3-gallate inhibits cyclooxygenase-2 expression in colon carcinogenesis. Mol Carcinog. 2006;45:309–319
  38. Lee MJ, Maliakal P, Chen L, Meng X, Bondoc FY, Prabhu S, et al. Pharmacokinetics of tea catechins after ingestion of green tea and (−)-epigallocatechin-3-gallate by humans: formation of different metabolites and individual variability. Cancer Epidemiol Biomarkers Prev. 2002;11:1025–1032
  39. Prior IA, Harding A, Yan J, Sluimer J, Parton RG, Hancock JF. GTP-dependent segregation of H-ras from lipid rafts is required for biological activity. Nat Cell Biol. 2001;3:368–375
  40. Garrean S, Gao XP, Brovkovych V, Shimizu J, Zhao YY, Vogel SM, et al. Caveolin-1 regulates NF-kappaB activation and lung inflammatory response to sepsis induced by lipopolysaccharide. J Immunol. 2006;177:4853–4860
  41. Chen HQ, Tannous M, Veluthakal R, Amin R, Kowluru A. Novel roles for palmitoylation of Ras in IL-1 beta-induced nitric oxide release and caspase 3 activation in insulin-secreting beta cells. Biochem Pharmacol. 2003;66:1681–1694

PII: S0955-2863(08)00052-1

doi: 10.1016/j.jnutbio.2008.02.004

The Journal of Nutritional Biochemistry
Volume 20, Issue 3 , Pages 202-209 , March 2009

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