« Previous
Next »
The Journal of Nutritional Biochemistry
Volume 20, Issue 1
, Pages 45-61
, January 2009
Phospholipidosis and down-regulation of the PI3-K/PDK-1/Akt signalling pathway are vitamin E inhibitable events associated with 7-ketocholesterol-induced apoptosis
References
- . Review of progress in sterol oxidations: 1987-1995. Lipids. 1996;31:453–457
- . Oxidized LDL-induced injury and apoptosis in atherosclerosis. Trends Cardiovasc Med. 2001;11:131–138
- . Oxysterols: modulators of cholesterol metabolism and other processes. Physiol Rev. 2000;80:361–554
- . Analysis of cholesterol oxidation products in biological samples. J AOAC Int. 2004;87:467–473
- Comparison of the cytotoxic, pro-oxidant and pro-inflammatory characteristics of different oxysterols. Cell Biol Toxicol. 2005;21:97–114
- Multiplexed flow cytometric analyses of pro- and anti-inflammatory cytokines in the culture media of oxysterol-treated human monocytic cells and in the sera of atherosclerotic patients. Cytometry A. 2006;69:359–373
- . Cytokines in atherosclerosis: pathogenic and regulatory pathways. Physiol Rev. 2006;86:515–581
- Cytotoxic oxysterols induce caspase-independent myelin figure formation and caspase-dependent polar lipid accumulation. Histochem Cell Biol. 2007;127:609–624
- Analysis of the fluorescence of monodansylcadaverine-positive cytoplasmic structures during 7-ketocholesterol-induced cell death. Anal Quant Cytol Histol. 2004;26:47–56
- . Biogenesis of multilamellar bodies via autophagy. Mol Biol Cell. 2000;11:255–268
- Analysis of oxidative processes and of myelin figure formation before and after the loss of mitochondrial potential during 7b-hydroxycholesterol and 7-ketocholesterol-induced apoptosis: comparison with various pro-apoptotic chemicals. Biochem Pharmacol. 2002;64:527–541
- . 7-ketocholesterol induces protein ubiquitination, myelin figure formation, and light chain 3 processing in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 2004;24:2296–2301
- . Autophagy delays sulindac sulfide-induced apoptosis in the human intestinal colon cancer cell line HT-29. Exp Cell Res. 2001;268:139–149
- . Distinct classes of phosphatidylinositol 3¢-kinases are involved in signaling pathways that control macro-autophagy in HT-29 cells. J Biol Chem. 2000;275:992–998
- . Cellular survival: a play in three Akts. Gene Dev. 1999;13:2905–2927
- . The nuclear phosphoinositide 3-kinase/Akt pathway: a new second messenger system. Biochim Biophys Acta. 2002;1584:73–80
- Involvement of a calcium-dependent dephosphorylation of BAD associated with the localization of Trpc-1 within lipid rafts in 7-ketocholesterol-induced THP-1 cell apoptosis. Cell Death Differ. 2004;11:897–905
- Impairment with various antioxidants of the loss of mitochondrial transmembrane potential and of the cytosolic release of cytochrome c occurring during 7-ketocholesterol-induced apoptosis. Free Radic Biol Med. 2000;28:743–753
- . AKT/protein kinase B regulation of BCL family members during oxysterol-induced apoptosis. J Biol Chem. 2004;279:1392–1399
- . Drug-induced phospholipidosis: are there functional consequences?. Exp Biol Med. 2001;226:825–830
- . Drug-induced phospholipidosis. FEBS Lett. 2006;580:5533–5540
- . Autophagic proteolysis: control and specificity. Histochem J. 1997;29:365–385
- . Use of fluorescently labeled caspase inhibitors as affinity labels to detect activated caspases. Hum Cell. 2002;15:1–12
- . Effects of caspase inhibitors (z-VAD-fmk, z-VDVAD-fmk) on Nile Red fluorescence pattern in 7-ketocholesterol-treated cells: investigation by flow cytometry and spectral imaging microscopy. Cytometry A. 2007;71:550–562
- Kinetics of plasma membrane and mitochondrial alterations in cells undergoing apoptosis. Cytometry. 1995;21:275–283
- . Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles. Eur J Cell Biol. 1995;66:3–14
- . A novel technique for mapping the lipid composition of atherosclerotic fatty streaks by en face fluorescence microscopy. J Histochem Cytochem. 1997;45:743–753
- 7-Ketocholesterol favors lipid accumulation and colocalizes with Nile Red positive cytoplasmic structures formed during 7-ketocholesterol-induced apoptosis: analysis by flow cytometry, FRET biphoton spectral imaging microscopy, and subcellular fractionation. Cytometry A. 2005;64:87–100
- . Altered lipid packing identifies apoptotic cells. Immunol Lett. 1993;36:283–288
- . Versatility of merocyanine 540 for the flow cytometric detection of apoptosis in human and murine cells. J Immunol Methods. 2002;61:129–139
- . Ceroid accumulation by murine peritoneal macrophages exposed to artificial lipoproteins: ultrastructural observations. Br J Exp Pathol. 1988;69:43–56
- . Lipofuscin and ceroid formation: the cellular recycling system. In: Porta EA editors. Lipofuscin and Ceroid Pigments. New York: Plenum Press; 1990;p. 3–15
- . Evaluation of lysosomal stability in living culture macrophages by cytofluorometry. Effect of silver lactate and hypotonic solutions. Virchows Arch - B: Cell Pathol. 1989;56:263–269
- . Lysosomal destabilisation during macrophage damage induced by cholesterol oxidation products. Free Radic Biol Med. 2000;28:208–218
- . The membrane fluidity concept revised by polarized fluorescence spectroscopy on different models membranes containing unsaturated lipids and sterols. Biochimie. 1989;71:23–32
- . A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem. 1957;226:497–509
- . Quantitative analysis of phospholipids by HPLC with a light scattering evaporating detector: application to raw materials for cosmetic use. J High Resolut Chromatogr. 1990;13:126–129
- Measurement of protein using bicinchoninic acid. Anal Biochem. 1985;150:76–85
- . The fine structure of ceroid in human atheroma. J Histochem Cytochem. 1968;15:732–736
- . The biochemistry of programmed cell death. FASEB J. 1995;9:1277–1287
- . Plasma phospholipid deposition in human serum and atherosclerotic lesions. Am J Physiol. 1995;181:527–531
- . Changes in the phospholipid composition of the arterial cell can result in severe atherosclerotic lesions. J Nutr Biochem. 2001;12:602–607
- . Vitamin E and the prevention of atherosclerosis. Int J Vitam Nutr Res. 2001;71:18–24
- Confocal analysis of phosphatidylserine externalization with the use of biotinylated annexin V revealed with streptavidin FITC, -europium, -phycoerythrin or -Texas Red in oxysterol-treated apoptotic cells. Anal Quant Cytol Histol. 2001;23:47–55
- . Biological membrane deterioration and associated quality losses in food tissues. Crit Rev Food Sci Nutr. 1991;30:487–6053
- . Phase transitions and fluidity characteristics of lipids and cell membranes. Q Rev Biophys. 1975;8:185–235
- . Lipid fluidity and membrane protein monitoring using 1,6-diphenyl-1,3,5-hexatriene. Biochim Biophys Acta. 1980;601:315–327
- The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway. J Biol Chem. 2001;276:35243–35246
- Inhibition of phosphatidylinositol 3¢-kinase/AKT signaling promotes apoptosis of primary effusion lymphoma cells. Clin Cancer Res. 2005;11:3102–3108
- . Activation of caspase-3 dependent and independent pathways during 7-ketocholesterol- and 7b-hydroxycholesterol-induced cell death: a morphological and biochemical study. J Biochem Mol Toxicol. 2005;19:311–326
- . Plasma cholesterol oxidation products (oxysterols) in human subjects fed a meal rich in oxysterols. J Food Sci. 1991;56:843–847
- . Dietary oxysterols are involved in plasma triglyceride rich lipoproteins, increase their susceptibility to oxidation and increase aortic cholesterol concentration in rabbits. J Lipid Res. 1998;39:1995–2004
- Characterization and comparison of the mode of cell death, apoptosis versus necrosis, induced by 7b-hydroxycholesterol and 7-ketocholesterol in the cells of the vascular wall. Arterioscler Thromb Vasc Biol. 1999;19:1190–1200
- . Inflammation and atherosclerosis: novel insight into plaque formation and destabilization. Stroke. 2006;37:1923–1932
- . Induction of apoptosis by cationic amphiphilic drugs amiodarone and imipramine. Drug Chem Toxicol. 2005;28:117–133
- The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages. Nat Cell Biol. 2003;5:781–792
- . Apoptotic death of inflammatory cells in human atheroma. Arterioscler Thromb Vasc Biol. 2001;21:1124–1130
- . Lipoapoptosis: its mechanism and its diseases. Biochim Biophys Acta. 2002;15:202–212
- . Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood. 1994;84:1415–1420
- . Molecular basis for the substrate specificity of protein kinase B; comparison with MAP kinase-1 and p70 S6 kinase. FEBS Lett. 1996;399:333–338
- . Inhibition of protein kinase B/Akt: implication for cancer therapy. Pharmacol Ther. 2002;93:243–251
- . Macrophage uptake of oxidized LDL inhibits lysosomal sphingomyelinase, thus causing the accumulation of unesterified cholesterol-sphingomyelin-rich particles in the lysosomes. A possible role for 7-ketocholesterol. J Lipid Res. 1995;15:1378–1387
- . Stimulation of CTP:phosphocholine cytidylyltransferase by free cholesterol loading of macrophages involves signaling through protein dephosphorylation. J Biol Chem. 1995;270:29894–29903
- . Lipid rafts and signal transduction. Nat rev. 2000;1:31–41
- . Vitamin E, oxidative stress, and inflammation. Annu Rev Nutr. 2005;25:151–174
- Vitamin E mediates cell signaling and regulation of gene expression. Ann N Y Acad Sci. 2004;1031:86–95
- . Non-oxidant activities of Vitamin E. Curr Med Chem. 2004;11:1113–1133
- Ceramide generation occurring during 7b-hydroxycholesterol- and 7-ketocholesterol-induced apoptosis is caspase independent and is not required to trigger cell death. Cell Death Differ. 2001;8:83–99
- . Structural interactions between vitamin E and polyunsaturated lipids. World Rev Nutr Diet. 1978;31:184–189
- . Vitamin E reduces accumulation of amiodarone and desethylamiodarone and inhibits phospholipidosis in cultured human cells. Biochem Pharmacol. 1995;49:1741–1745
- Protein phosphatase 2A regulates bim expression via the Akt/FKHRL1 signaling pathway in amyloid-beta peptide-induced cerebrovascular endothelial cell death. J Neurosci. 2006;26:2290–2299
- . Vitamin E inhibits endotoxin-mediated transport of phosphatases to lipid rafts. Shock. 2007;27:19–24
- Oxysterol-induced osteoblastic differentiation of pluripotent mesenchymal cells is mediated through a PKC- and PKA-dependent pathway. J Cell Biochem. 2007;100:1131–1145
- Association of polymorphism of P22(phox) C242T, plasma levels of Vitamin E, and smoking with coronary heart disease in China. Am Heart J. 2007;153:640–646
- Alterations in plasma vitamin E distribution in type 2 diabetic patients with elevated plasma phospholipid transfer protein activity. Diabetes. 2004;53:2633–2639
- . Induction of similar features of apoptosis in human and bovine vascular endothelial cells treated by 7-ketocholesterol. J Pathol. 1997;183:330–338
- NAD(P)H oxidase Nox-4 mediates 7-ketocholesterol-induced endoplasmic reticulum stress and apoptosis in human aortic smooth muscle cells. Mol Cell Biol. 2004;24:10703–10717
PII: S0955-2863(08)00002-8
doi: 10.1016/j.jnutbio.2007.12.001
© 2009 Elsevier Inc. All rights reserved.
« Previous
Next »
The Journal of Nutritional Biochemistry
Volume 20, Issue 1
, Pages 45-61
, January 2009
