The Journal of Nutritional Biochemistry
Volume 19, Issue 11 , Pages 727-731 , November 2008

Dietary oleic acid and adipocyte lipolytic activity in culture

Received 30 May 2007 ,Accepted 13 September 2007.

References 

  1. Forouhi NG, Jenkinson G, Thomas EL, Mullick S, Mierisova S, Bhonsle U, et al. Relation of triglyceride stores in skeletal muscle cells to central obesity and insulin sensitivity in European and South Asian men. Diabetologia. 1999;42:932–935
  2. Krssak M, Falk Petersen K, Dresner A, DiPietro L, Vogel SM, Rothman DL, et al. Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study. Diabetologia. 1999;42:113–116
  3. Holm C. Molecular mechanisms regulating hormone-sensitive lipase and lipolysis. Biochem Soc Trans. 2003;31:1120–1124
  4. Guzman M, Lo Verme J, Fu J, Oveisi F, Blazquez C, Piomelli D. Oleoylethanolamide stimulates lipolysis by activating the nuclear receptor peroxisome proliferator-activated receptor alpha (PPAR-alpha). J Biol Chem. 2004;279:27849–27854
  5. Schoonjans K, Peinado-Onsurbe J, Lefebvre AM, Heyman RA, Briggs M, Deeb S, et al. PPARalpha and PPARgamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene. EMBO J. 1996;15:5336–5348
  6. Wang MY, Lee Y, Unger RH. Novel form of lipolysis induced by leptin. J Biol Chem. 1999;274:17541–17544
  7. Soriguer F, Moreno F, Rojo-Martinez G, Garcia-Fuentes E, Tinahones F, Gomez-Zumaquero JM, et al. Monounsaturated n-9 fatty acids and adipocyte lipolysis in rats. Br J Nutr. 2003;90:1015–1022
  8. Koh EH, Kim MS, Park JY, Kim HS, Youn JY, Park HS, et al. Peroxisome proliferator-activated receptor (PPAR)-alpha activation prevents diabetes in OLETF rats: comparison with PPAR-gamma activation. Diabetes. 2003;52:2331–2337
  9. Srivastava RA, Jahagirdar R, Azhar S, Sharma S, Bisgaier CL. Peroxisome proliferator-activated receptor-alpha selective ligand reduces adiposity, improves insulin sensitivity and inhibits atherosclerosis in LDL receptor-deficient mice. Mol Cell Biochem. 2006;285:35–50
  10. Reeves PG, Nielsen FH, Fahey GC. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr. 1993;123:1939–1951
  11. Hamilton S, Hamilton RJ, Sewel PA. Extraction of lipids and derivative formation. Lipid anlysis. A practical approach. In:  Hamilton RJ,  Hamilton S editor. Oxford University: Press; 1992;
  12. Rodbell M. Metabolism of isolated fat cells. VI. The effects of insulin, lipolytic hormones, and theophylline on glucose transport and metabolism in “ghosts”. J Biol Chem. 1967;242:5751–5756
  13. Goldrick RB. Morphological changes in the adipocyte during fat deposition and mobilization. Am J Physiol. 1967;212:777–782
  14. DiGirolamo M, Fine JB, Tagra K, Rossmanith R. Qualitative regional differences in adipose tissue growth and cellularity in male Wistar rats fed ad libitum. Am J Physiol. 1998;274:R1460–R1467
  15. In:  Altman DG editors. Practical statistics for medical research. London: Chapman & Hall; 1991;p. 218–223
  16. Frayn K. Adipose tissue as a buffer for daily lipid flux. Diabetologia. 2002;45:1201–1210
  17. Kelley DE. Skeletal muscle fat oxidation: timing and flexibility are everything. J Clin Invest. 2005;115:1699–1702
  18. McGarry JD. Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes. Diabetes. 2002;51:7–18
  19. Storlien L, Oakes ND, Kelley DE. Metabolic flexibility. Proc Nutr Soc. 2004;63:363–368
  20. Lee JS, Pinnamaneni SK, Eo SJ, Cho IH, Pyo JH, Kim CK, et al. Saturated, but not n-6 polyunsaturated, fatty acids induce insulin resistance: role of intramuscular accumulation of lipid metabolites. J Appl Physiol. 2006;100:1467–1474
  21. Stich V, Berlan M. Physiological regulation of NEFA availability: lipolysis pathway. Proc Nutr Soc. 2004;63:369–374
  22. Kabir M, Catalano KJ, Ananthnarayan S, Kim SP, Van Citters GW, Dea MK, et al. Molecular evidence supporting the portal theory: a causative link between visceral adiposity and hepatic insulin resistance. Am J Physiol Endocrinol Metab. 2005;288:E454–E461
  23. Large V, Arner P. Regulation of lipolysis in humans. Pathophysiological modulation in obesity, diabetes, and hyperlipidaemia. Diabetes Metab. 1998;24:409–418

 This study was undertaken with finance from the Fondo de Investigación Sanitaria of the Instituto de Salud Carlos III (PI021480 and Metabolism and Nutrition Network RCMYN C03-08) and Junta de Andalucía (02/03, 125/02, 115/02) and the Asociación Maimónides. The group belongs to the CIBER of Physiopathology of Obesity and Nutrition (CB06/03/0018) and RETICS of Diabetes and Metabolism (RD06/0015/008) of the Instituto de Salud Carlos III.

PII: S0955-2863(07)00244-6

doi: 10.1016/j.jnutbio.2007.09.007

The Journal of Nutritional Biochemistry
Volume 19, Issue 11 , Pages 727-731 , November 2008