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The Journal of Nutritional Biochemistry
Volume 19, Issue 7
, Pages 417-437
, July 2008
Modulation of enzymatic activities by n-3 polyunsaturated fatty acids to support cardiovascular health
References
- . Overview of evolutionary aspects of omega 3 fatty acids in the diet. World Rev Nutr Diet. 1998;83:1–11
- . The composition of the Eskimo food in north western Greenland. Am J Clin Nutr. 1980;33:2657–2661
- . Fatty acid composition of the plasma lipids in Greenland Eskimos. Am J Clin Nutr. 1975;28:958–966
- Longchain serum fatty acids and risk of thyroid cancer: a population-based case-control study in Norway. [erratum appears in Cancer Causes Control 1995 Mar; 6(2):182] Cancer Causes Control. 1994;5:433–439
- . Fish consumption and mortality from coronary heart disease. N Engl J Med. 1985;313:820
- . Fish consumption and mortality from coronary heart disease. Br Med J Clin Res Ed. 1986;293:426
- . Dietary factors associated with a low risk of colon cancer in coloured west coast fishermen. S Afr Med J. 1997;87:152–158
- . Eicosapentaenoic and docosapentaenoic acids are the principal products of alpha-linolenic acid metabolism in young men*. [see comment] Br J Nutr. 2002;88:355–363
- . Conversion of alpha-linolenic acid to eicosapentaenoic, docosapentaenoic and docosahexaenoic acids in young women. [see comment] Br J Nutr. 2002;88:411–420
- . Flaxseed oil increases the plasma concentrations of cardioprotective (n-3) fatty acids in humans. J Nutr. 2006;136:83–87
- Fish consumption and risk of sudden cardiac death. JAMA. 1998;279:23–28
- Fish consumption and the 30-year risk of fatal myocardial infarction. N Engl J Med. 1997;336:1046–1053
- . The composition of food consumed by Greenland Eskimos. Acta Med Scand. 1976;200:69–73
- Prevention of fatal arrhythmias in high-risk subjects by fish oil n-3 fatty acid intake. Circulation. 2005;112:2762–2768
- Mediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart disease. [see comment] [erratum appears in Lancet 1995 Mar 18;345(8951):738] Lancet. 1994;343:1454–1459
- Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico. [see comment] [erratum appears in Lancet 2001 Feb 24;357(9256):642] Lancet. 1999;354:447–455
- Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: diet and reinfarction trial (DART). [see comments] Lancet. 1989;2:757–761
- Diet and lifestyle recommendations revision 2006: a scientific statement from the American Heart Association Nutrition Committee. [erratum appears in Circulation. 2006 Jul 4;114(1):e27] Circulation. 2006;114:82–96
- . n-3 fatty acids and lipoproteins: comparison of results from human and animal studies. Lipids. 1996;31:243–252
- Purified eicosapentaenoic and docosahexaenoic acids have differential effects on serum lipids and lipoproteins, LDL particle size, glucose, and insulin in mildly hyperlipidemic men. Am J Clin Nutr. 2000;71:1085–1094
- Safety and efficacy of Omacor in severe hypertriglyceridemia. J Cardiovasc Risk. 1997;4:385–391
- Soluble cell adhesion molecules in hypertriglyceridemia and potential significance on monocyte adhesion. Arterioscler Thromb Vasc Biol. 1998;18:723–731
- . Prescription omega-3 fatty acids for the treatment of hypertriglyceridemia. Am J Health Syst Pharm. 2007;64:595–605
- . Effect of dietary supplementation with n-3 fatty acids on coronary artery bypass graft patency. Am J Cardiol. 1996;77:31–36
- Association of n-3 polyunsaturated fatty acids with stability of atherosclerotic plaques: a randomised controlled trial. Lancet. 2003;361:477–485
- . The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature. 1993;362:801–809
- . Interactions between dietary fat, fish, and fish oils and their effects on platelet function in men at risk of cardiovascular disease. Arterioscler Thromb Vasc Biol. 1997;17:279–286
- . Hemostatic factors and platelet aggregation after a fish-enriched diet or fish oil or docosahexaenoic acid supplementation. Prostaglandins Leukot Essent Fatty Acids. 1997;57:419–421
- Relationship of increased levels of circulating intercellular adhesion molecule 1 after heart transplantation to rejection: human leukocyte antigen mismatch and survival. J Heart Lung Transplant. 1994;13:597–603
- . Circulating adhesion molecules in disease. [see comment] Immunol Today. 1993;14:506–512
- . Fatty acid modulation of endothelial activation. Am J Clin Nutr. 2000;71:213S–223S
- . Long-term treatment with eicosapentaenoic acid augments both nitric oxide-mediated and non-nitric oxide-mediated endothelium-dependent forearm vasodilatation in patients with coronary artery disease. J Cardiovasc Pharmacol. 1999;33:633–640
- . Blood pressure response to fish oil supplementation: metaregression analysis of randomized trials. J Hypertens. 2002;20:1493–1499
- . Omega-3 fatty acids and hypertension in humans. Clin Exp Pharmacol Physiol. 2006;33:842–846
- . Intracellular free calcium concentration and thromboxane A2 formation of vascular smooth muscle cells are influenced by fish oil and n-3 eicosapentaenoic acid. Scand J Clin Lab Invest. 1991;51:541–547
- . The cardiac sarcoplasmic reticulum: filled with Ca2+ and surprises. [comment] Circ Res. 2007;100:5–6
- . Remodelling Ca2+ signalling systems and cardiac hypertrophy. Biochem Soc Trans. 2006;34:228–231
- . Calcium microdomains: organization and function. Cell Calcium. 2006;40:405–412
- . Effects of dietary cod liver oil on fatty-acid composition and calcium transport in isolated adult rat ventricular myocytes and on the response of isolated hearts to ischemia and reperfusion. Can J Physiol Pharmacol. 1987;65:201–209
- . Ca2+–Mg2+ ATPase of mouse cardiac sarcoplasmic reticulum is affected by membrane n-6 and n-3 polyunsaturated fatty acid content. J Nutr. 1989;119:364–372
- . Protective effect of eicosapentaenoic acid on ouabain toxicity in neonatal rat cardiac myocytes. Proc Natl Acad Sci U S A. 1990;87:7834–7838
- . Influence of dietary lipids on arrhythmias and infarction after coronary artery ligation in rats. Can J Physiol Pharmacol. 1985;63:1411–1417
- . The nature of the transport adenosine triphosphatase–digitalis complex. VII. Characteristics of ouabagenin–Na+,K+-adenosine triphosphatase interaction. J Pharmacol Exp Ther. 1974;189:434–444
- . Modulation of dihydropyridine-sensitive calcium channels in heart cells by fish oil fatty acids. Proc Natl Acad Sci U S A. 1992;89:1760–1764
- . Omega-3 fatty acids and prevention of ventricular fibrillation. Prostaglandins Leukot Essent Fatty Acids. 1995;52:197–198
- Effects of docosahexaenoic acid on calcium pathway in adult rat cardiomyocytes. Life Sci. 2002;71:993–1004
- . Inhibition by docosahexaenoic acid of receptor-mediated Ca(2+) influx in rat vascular smooth muscle cells stimulated with 5-hydroxytryptamine. Eur J Pharmacol. 2001;427:195–201
- Effect of docosahexaenoic acid on intracellular calcium dynamics in vascular smooth muscle cells from normotensive and genetically hypertensive rats. Res Commun Mol Pathol Pharmacol. 1998;102:29–42
- . Suppression of voltage-gated L-type Ca2+ currents by polyunsaturated fatty acids in adult and neonatal rat ventricular myocytes. Proc Natl Acad Sci U S A. 1997;94:4182–4187
- . External blockade of the major cardiac delayed-rectifier K+ channel (Kv1.5) by polyunsaturated fatty acids. Proc Natl Acad Sci U S A. 1994;91:1937–1941
- . Free, long-chain, polyunsaturated fatty acids reduce membrane electrical excitability in neonatal rat cardiac myocytes. Proc Natl Acad Sci U S A. 1995;92:3997–4001
- . Prevention of ischemia-induced ventricular fibrillation by omega 3 fatty acids. Proc Natl Acad Sci U S A. 1994;91:4427–4430
- . Inhibition of sarcoplasmic reticulum function by polyunsaturated fatty acids in intact, isolated myocytes from rat ventricular muscle. J Physiol. 2000;523(Pt 2):367–375
- . Partitioning of polyunsaturated fatty acids, which prevent cardiac arrhythmias, into phospholipid cell membranes. J Lipid Res. 2001;42:346–351
- . Antiarrhythmic effects of polyunsaturated fatty acids. Recent studies. Circulation. 1996;94:1774–1780
- Single point mutations affect fatty acid block of human myocardial sodium channel alpha subunit Na+ channels. Proc Natl Acad Sci U S A. 2001;98:3606–3611
- Potent block of inactivation-deficient Na+ channels by n-3 polyunsaturated fatty acids. Am J Physiol— Cell Physiol. 2006;290:C362–C370
- . Effects of eicosapentaenoic acid on cardiac SR Ca(2+)-release and ryanodine receptor function. Cardiovasc Res. 2003;60:337–346
- Effects of docosahexaenoic acid on [Ca(2+)](i) increase induced by doxorubicin in ventricular rat cardiomyocytes. Life Sci. 2002;71:1905–1916
- . Suppression of calcium sparks in rat ventricular myocytes and direct inhibition of sheep cardiac RyR channels by EPA, DHA and oleic acid. J Membr Biol. 2003;196:95–103
- . Modulation of ryanodine binding to the cardiac Ca2+ release channel by arachidonic acid. J Mol Cell Cardiol. 1996;28:43–51
- . Phosphoinositide-generated messengers in cardiac signal transduction. Mol Cell Biochem. 1996;157:5–14
- . Regulation of phosphoinositide-specific phospholipase C. Annu Rev Biochem. 2001;70:281–312
- . Different intracellular localization of inositol 1,4,5-trisphosphate and ryanodine receptors in cardiomyocytes. J Biol Chem. 1993;268:3499–3506
- Phospholipase C-delta1 rescues intracellular Ca2+ overload in ischemic heart and hypoxic neonatal cardiomyocytes. J Steroid Biochem Mol Biol. 2004;91:131–138
- . PLC-epsilon: a shared effector protein in Ras-, Rho-, and G alpha beta gamma-mediated signaling. Mol Interv. 2003;3:273–280
- . Leukocyte adhesion molecules on the vascular endothelium: their role in the pathogenesis of cardiovascular disease and the mechanisms underlying their expression. J Cardiovasc Pharmacol. 1993;22(Suppl 4):S37–S44
- . Mechanical stress mechanisms and the cell. An endothelial paradigm. Circ Res. 1993;72:239–245
- . Acute tissue-type plasminogen activator release in human microvascular endothelial cells: the roles of Galphaq, PLC-beta, IP3 and 5,6-epoxyeicosatrienoic acid. Thromb Haemost. 2007;97:263–271
- . The role of phospholipase C and phosphatidylinositol 3-kinase in vascular smooth muscle cell migration and proliferation. J Surg Res. 2004;120:256–265
- . Ca2+ channel–sarcoplasmic reticulum coupling: a mechanism of arterial myocyte contraction without Ca2+ influx. EMBO J. 2003;22:4337–4345
- . The cellular basis of contraction and relaxation in cardiac and vascular smooth muscle. Am Heart J. 1991;121:961–968
- . Molecular and biological effects of hemodynamics on vascular cells. Front Biosci. 2004;9:3276–3285
- . Inhibition of PLC improves postischemic recovery in isolated rat heart. Am J Physiol Heart Circ Physiol. 2004;287:H2598–H2605
- . Phospholipase C inhibitors attenuate arrhythmias induced by kappa-receptor stimulation in the isolated rat heart. J Mol Cell Cardiol. 1998;30:2103–2110
- . Effects of dietary fat supplementation on inositol phosphate release and metabolism in rat left atria. J Mol Cell Cardiol. 1995;27:867–871
- . Suppression of inositol phosphate release by cardiac myocytes isolated from fish oil-fed pigs. Mol Cell Biochem. 2000;215:57–64
- . Eicosapentaenoic acid incorporation in membrane phospholipids modulates receptor-mediated phospholipase C and membrane fluidity in rat ventricular myocytes in culture. J Mol Cell Cardiol. 1996;28:1097–1108
- . Docosahexaenoic acid selectively attenuates induction of vascular cell adhesion molecule-1 and subsequent monocytic cell adhesion to human endothelial cells stimulated by tumor necrosis factor-alpha. Arterioscler Thromb Vasc Biol. 1995;15:622–628
- . Specialization in membrane structure and metabolism with respect to polyunsaturated lipids. Prog Clin Biol Res. 1988;282:319–333
- . Oxidative stress and redox regulation of phospholipase D in myocardial disease. Free Radic Biol Med. 2006;41:349–361
- . Intracellular localization of phospholipase D1 in mammalian cells. Mol Biol Cell. 2001;12:943–955
- Cardiac phospholipase D2 localizes to sarcolemmal membranes and is inhibited by alpha-actinin in an ADP-ribosylation factor-reversible manner. J Biol Chem. 2000;275:21295–21301
- . Phosphatidic acid increases intracellular free Ca2+ and cardiac contractile force. Am J Physiol. 1996;271:H651–H659
- . Responses of heart function and intracellular free Ca2+ to phosphatidic acid in chronic diabetes. Can J Cardiol. 1996;12:1092–1098
- . Phosphatidic acid: a potential signal transducer for cardiac hypertrophy. J Mol Cell Cardiol. 1997;29:2865–2871
- . Activation of phospholipase Cepsilon by free fatty acids and cross talk with phospholipase D and phospholipase A2. Biochemistry. 2006;45:10987–10997
- . Protein kinase C and phospholipase D: intimate interactions in intracellular signaling. Cell Mol Life Sci. 2005;62:1448–1461
- . Expression of phospholipase D isozymes in scar and viable tissue in congestive heart failure due to myocardial infarction. J Cell Mol Med. 2004;8:526–536
- . Structure–activity relationship of the effect of cis-unsaturated fatty acids on heart sarcolemmal phospholipase D activity. Prostaglandins Leukot Essent Fatty Acids. 1995;52:167–171
- The mechanism of docosahexaenoic acid-induced phospholipase D activation in human lymphocytes involves exclusion of the enzyme from lipid rafts. J Biol Chem. 2002;277:39368–39378[Published online as 10.1074/jbc.M202376200]
- . A role for docosahexaenoic acid-containing phosphatidylethanolamine in lipid raft phase separations. Biophys J. 2004;87:1752–1766
- . Oleate stimulation of diacylglycerol formation from phosphatidylcholine through effects on phospholipase D and phosphatidate phosphohydrolase. Eur J Biochem. 1992;210:601–607
- . A novel mechanism for the store-operated calcium influx pathway. Nat Cell Biol. 2004;6:113–120
- . Phospholipase A2: a key regulator of inflammatory signalling and a connector to fibrosis development in atherosclerosis. Biochim Biophys Acta. 2006;1761:1309–1316
- . Recent insights into the role of prostanoids in atherosclerotic vascular disease. Curr Vasc Pharmacol. 2006;4:395–408
- . More selective ligands at eicosanoid receptor subtypes improve prospects in inflammatory and cardiovascular research. Trends Pharmacol Sci. 1990;11:301–304
- . Physiological and pathophysiological roles of eicosanoids in the microcirculation. Cardiovasc Res. 1996;32:720–732
- . Phospholipase A2 enzymes. Prostaglandins Other Lipid Mediat. 2002;68–69:3–58
- . The phospholipase A2 superfamily and its group numbering system. Biochim Biophys Acta. 2006;1761:1246–1259
- . Mammalian secreted phospholipases A2 and their pathophysiological significance in inflammatory diseases. Curr Mol Med. 2001;1:739–754
- . Interleukin-1beta-induced type IIA secreted phospholipase A2 gene expression and extracellular activity in rat vascular endothelial cells. Tissue Cell. 2001;33:233–240
- . Interferon-gamma induces secretory group IIA phospholipase A2 in human arterial smooth muscle cells. Involvement of cell differentiation, STAT-3 activation, and modulation by other cytokines. J Biol Chem. 2000;275:22895–22904
- . Cytokine-stimulated secretion of group II phospholipase A2 by rat mesangial cells. Its contribution to arachidonic acid release and prostaglandin synthesis by cultured rat glomerular cells. J Clin Invest. 1993;92:2516–2523
- . Enhanced expression of group II phospholipase A2 gene in the tissues of endotoxin shock rats and its suppression by glucocorticoid. FEBS Lett. 1990;273:23–26
- . Cytosolic phospholipase A2 is required for cytokine-induced expression of type IIA secretory phospholipase A2 that mediates optimal cyclooxygenase-2-dependent delayed prostaglandin E2 generation in rat 3Y1 fibroblasts. J Biol Chem. 1998;273:1733–1740
- . Regulatory functions of phospholipase A2. Crit Rev Immunol. 1997;17:225–283
- . Secretory phospholipase A2 enzymes in atherogenesis. Curr Opin Lipidol. 2005;16:341–344
- . New phospholipase A(2) isozymes with a potential role in atherosclerosis. Curr Opin Lipidol. 2003;14:431–436
- . The role of calcium and phosphorylation of cytosolic phospholipase A2 in regulating arachidonic acid release in macrophages. J Biol Chem. 1998;273:8203–8211
- Identification of phosphorylation sites of human 85-kDa cytosolic phospholipase A2 expressed in insect cells and present in human monocytes. J Biol Chem. 1996;271:6987–6997
- . Substrate specificities and properties of human phospholipases A2 in a mixed vesicle model. J Biol Chem. 1992;267:18342–18348
- . Processive interfacial catalysis by mammalian 85-kilodalton phospholipase A2 enzymes on product-containing vesicles: application to the determination of substrate preferences. Biochemistry. 1993;32:5949–5958
- A novel arachidonic acid-selective cytosolic PLA2 contains a Ca(2+)-dependent translocation domain with homology to PKC and GAP. Cell. 1991;65:1043–1051
- . A novel cytosolic calcium-independent phospholipase A2 contains eight ankyrin motifs. J Biol Chem. 1997;272:8567–8575
- . The cardiac beta2-adrenergic signalling a new role for the cPLA2. Cell Signal. 2005;17:141–152
- . Eicosapentaenoic and docosahexaenoic acids in cultured rat ventricular myocytes and hypoxia-induced alterations of phospholipase-A activity. Mol Cell Biochem. 1992;116:75–78
- . Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2. J Biol Chem. 1996;271:33157–33160
- . Cytochrome P450 and arachidonic acid bioactivation. Molecular and functional properties of the arachidonate monooxygenase. J Lipid Res. 2000;41:163–181
- Cyclooxygenase in biology and disease. [see comment] FASEB J. 1998;12:1063–1073
- . Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation. Science. 1983;220:568–575
- . Prostaglandins and leukotrienes: advances in eicosanoid biology. Science. 2001;294:1871–1875
- . Vascular protective effects of cytochrome p450 epoxygenase-derived eicosanoids. Arch Biochem Biophys. 2005;433:413–420
- . Cytochrome P450 enzymes: central players in cardiovascular health and disease. Pharmacol Ther. 2006;112:564–587
- . The 5 lipoxygenase system in the vasculature: emerging role in health and disease. Mol Cell Endocrinol. 2006;252:201–206
- COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression. [see comment] Proc Natl Acad Sci U S A. 2002;99:13926–13931
- . Acceleration of atherogenesis by COX-1-dependent prostanoid formation in low density lipoprotein receptor knockout mice. Proc Natl Acad Sci U S A. 2001;98:3358–3363
- . Effect of serotonin, thromboxane A2, and specific receptor antagonists on vascular smooth muscle cell proliferation. Circulation. 1997;96:2280–2286
- Overexpression of functionally coupled cyclooxygenase-2 and prostaglandin E synthase in symptomatic atherosclerotic plaques as a basis of prostaglandin E(2)-dependent plaque instability. Circulation. 2001;104:921–927
- Cyclooxygenase-2 is widely expressed in atherosclerotic lesions affecting native and transplanted human coronary arteries and colocalizes with inducible nitric oxide synthase and nitrotyrosine particularly in macrophages. Arterioscler Thromb Vasc Biol. 1999;19:646–655
- . Dietary n-3 fatty acids accelerate catabolism of leukotriene B4 in human granulocytes. Biochim Biophys Acta. 1993;1166:20–24
- Fatty acid substrate specificities of human prostaglandin-endoperoxide H synthase-1 and -2. Formation of 12-hydroxy-(9Z, 13E/Z, 15Z)-octadecatrienoic acids from alpha-linolenic acid. J Biol Chem. 1995;270:19330–19336
- . Fatty acids and immune responses — a new perspective in searching for clues to mechanism. Annu Rev Nutr. 2000;20:431–456
- . Lipids in vascular function. Lipids. 1999;34(Suppl):S13–S18
- . Docosahexaenoic acid is a strong inhibitor of prostaglandin but not leukotriene biosynthesis. Proc Natl Acad Sci U S A. 1983;80:3581–3584
- . Omega-3 and omega-6 essential fatty acids and cyclooxygenase pathways. FASEB J. 2006;20:576;[abstract]
- Cox-2 inhibitory effects of naturally occurring and modified fatty acids. J Nat Prod. 2001;64:745–749
- . Eicosapentaenoic acid and prostacyclin production by cultured human endothelial cells. J Lipid Res. 1983;24:1595–1604
- Inhibition by eicosapentaenoic acid of IL-1beta-induced PGHS-2 expression in human microvascular endothelial cells: involvement of lipoxygenase-derived metabolites and p38 MAPK pathway. Biochim Biophys Acta. 2003;1631:77–84
- Differential modulation of Toll-like receptors by fatty acids: preferential inhibition by n-3 polyunsaturated fatty acids. J Lipid Res. 2003;44:479–486
- . Docosahexaenoic acid enhances cyclooxygenase-2 induction by facilitating p44/42, but not p38, mitogen-activated protein kinase activation in rat vascular smooth muscle cells. J Pharmacol Sci. 2005;99:113–116
- . Differential effects of long chain n-3 fatty acids on the expression of PGH synthase isoforms in bovine aortic endothelial cells. Prostaglandins Leukot Essent Fatty Acids. 1999;60:363–365
- . Inhibition of prostaglandin biosynthesis by eicosapentaenoic acid. Prostaglandins Med. 1979;3:269–278
- . Uptake, release and metabolism of docosahexaenoic acid (DHA, c22:6 omega 3) in human platelets and neutrophils. Biochem Biophys Res Commun. 1984;120:907–918
- . Leukotrienes and other products of the 5-lipoxygenase pathway. Biochemistry and relation to pathobiology in human diseases. N Engl J Med. 1990;323:645–655
- . From asthma to atherosclerosis-5-lipoxygenase, leukotrienes, and inflammation. [comment] N Engl J Med. 2004;350:4–7
- . Leukotriene receptors in atherosclerosis. Ann Med. 2006;38:493–502
- . Leukotriene B: a potential mediator of inflammation. J Pharm Pharmacol. 1980;32:517–518
- . The mechanism of vascular leakage induced by leukotriene E4. Endothelial contraction. Am J Pathol. 1987;126:19–24
- . Biological profile of leukotrienes C4 and D4. Acta Physiol Scand. 1980;110:331–333
- . Local effects of synthetic leukotrienes (LTC4, LTD4, LTE4, and LTB4) in human skin. J Invest Dermatol. 1983;80:115–119
- Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response. Proc Natl Acad Sci U S A. 1981;78:3887–3891
- International Union of Pharmacology XXXVII. Nomenclature for leukotriene and lipoxin receptors. Pharmacol Rev. 2003;55:195–227
- . Leukotriene B5 is formed in human neutrophils after dietary supplementation with eicosapentaenoic acid. Proc Natl Acad Sci U S A. 1985;82:1540–1543
- . The effect of eicosapentaenoic acid on leukotriene B production by human neutrophils. J Biol Chem. 1984;259:7615–7621
- . Characterization and biologic properties of 5,12-dihydroxy derivatives of eicosapentaenoic acid, including leukotriene B5 and the double lipoxygenase product. J Biol Chem. 1984;259:2383–2389
- Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesis. Proc Natl Acad Sci U S A. 2003;100:1238–1243
- Association between 5-lipoxygenase expression and plaque instability in humans. Arterioscler Thromb Vasc Biol. 2005;25:1665–1670
- . Functional characteristics of cysteinyl-leukotriene receptor subtypes. Life Sci. 2002;71:611–622
- . Leukotriene B4 signaling through NF-kappaB-dependent BLT1 receptors on vascular smooth muscle cells in atherosclerosis and intimal hyperplasia. Proc Natl Acad Sci U S A. 2005;102:17501–17506
- Differential leukotriene receptor expression and calcium responses in endothelial cells and macrophages indicate 5-lipoxygenase-dependent circuits of inflammation and atherogenesis. Arterioscler Thromb Vasc Biol. 2003;23:e32–e36
- Influence of atherosclerosis on the vascular reactivity of isolated human epicardial coronary arteries to leukotriene C4. Cardioscience. 1993;4:47–54
- Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability. Proc Natl Acad Sci U S A. 2006;103:8161–8166
- Leukotriene receptors on human pulmonary vascular endothelium. Br J Pharmacol. 1995;115:1382–1386
- Prostacyclin modulation of contractions of the human pulmonary artery by cysteinyl-leukotrienes. Eur J Pharmacol. 2000;401:389–395
- . Modulation of vascular tone and reactivity by nitric oxide in porcine pulmonary arteries and veins. Acta Physiol Scand. 2002;174:9–15
- Cysteinyl leukotriene 2 receptor and protease-activated receptor 1 activate strongly correlated early genes in human endothelial cells. Proc Natl Acad Sci U S A. 2006;103:6326–6331
- Functional characterization of cysteinyl leukotriene CysLT(2) receptor on human coronary artery smooth muscle cells. Biochem Biophys Res Commun. 2001;287:1088–1092
- Free arachidonic versus eicosapentaenoic acid differentially influences the potency of bacterial exotoxins to provoke myocardial depression in isolated rat hearts. Crit Care Med. 2006;34:118–126
- . Impact of arachidonic versus eicosapentaenoic acid on exotonin-induced lung vascular leakage: relation to 4-series versus 5-series leukotriene generation. Am J Respir Crit Care Med. 1997;155:513–519
- . Comparative effect of leukotriene B4 and leukotriene B5 on calcium mobilization in human neutrophils. Prostaglandins Leukot Essent Fatty Acids. 1988;34:47–50
- Omega-3 lipid infusion in a heart allotransplant model. Shift in fatty acid and lipid mediator profiles and prolongation of transplant survival. Circulation. 1996;93:365–371
- . Novel chemical mediators in the resolution of inflammation: resolvins and protectins. Anesthesiol Clin. 2006;24:341–364
- . The contributions of aspirin and microbial oxygenase to the biosynthesis of anti-inflammatory resolvins: novel oxygenase products from omega-3 polyunsaturated fatty acids. Biochem Biophys Res Commun. 2005;338:149–157
- . Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing. J Exp Med. 2000;192:1197–1204
- . Contribution of cytochrome P-450 4A1 and 4A2 to vascular 20-hydroxyeicosatetraenoic acid synthesis in rat kidneys. Am J Physiol. 1999;276:F246–F253
- . EET homologs potently dilate coronary microvessels and activate BK(Ca) channels. Am J Physiol Heart Circ Physiol. 2001;280:H2430–H2440
- . P-450 metabolites of arachidonic acid in the control of cardiovascular function. Physiol Rev. 2002;82:131–185
- . Mechanism of action of cerebral epoxyeicosatrienoic acids on cerebral arterial smooth muscle. Am J Physiol. 1992;263:H519–H525
- . Cytochrome p-450 epoxygenase metabolites of docosahexaenoate potently dilate coronary arterioles by activating large-conductance calcium-activated potassium channels. J Pharmacol Exp Ther. 2002;303:768–776
- Oxygenation of omega-3 fatty acids by human cytochrome P450 4F3B: effect on 20-hydroxyeicosatetraenoic acid production. Prostaglandins Leukot Essent Fatty Acids. 2006;75:169–177
- . Modulation of cyclic nucleotide phosphodiesterase by dietary fats in rat heart. Lipids. 1992;27:746–754
- . The effect of dietary lipid on the binding of [3H] dihydroalprenolol and adenylate cyclase activity in rat atria. J Pharmacol Exp Ther. 1981;219:625–631
- . Effect of dietary polyunsaturated fatty acids on contraction and relaxation of rat femoral resistance arteries. J Cardiovasc Pharmacol. 1994;23:92–98
- . Polyunsaturated fatty acids in heart muscle and alpha 1-adrenoceptor binding properties. Biochim Biophys Acta. 1993;1178:49–54
- . Blood pressure and vascular reactivity changes in spontaneously hypertensive rats fed fish oil. Br J Pharmacol. 1991;102:991–997
- . Cardiac adrenoceptors: physiological and pathophysiological relevance. J Pharmacol Sci. 2006;100:323–337
- . Effect of docosahexaenoic acid and eicosapentaenoic acid in the phospholipids of rat heart muscle cells on adrenoceptor responsiveness and mechanism. J Mol Cell Cardiol. 1995;27:2507–2520
- . Membrane docosahexaenoic acid vs. eicosapentaenoic acid and the beating function of the cardiomyocyte and its regulation through the adrenergic receptors. Lipids. 1996;31(Suppl):S205–S210
- . Evidence that free polyunsaturated fatty acids modify Na+ channels by directly binding to the channel proteins. Proc Natl Acad Sci U S A. 1996;93:3542–3546
- . Mechanism of inhibition of a tumor lipid-mobilizing factor by eicosapentaenoic acid. Cancer Res. 1998;58:4827–4831
- . Polyunsaturated fatty acids in cultured cardiomyocytes: effect on physiology and beta-adrenoceptor function. Am J Physiol. 1992;262:H451–H456
- . Regulation of phosphodiesterase 3 and inducible cAMP early repressor in the heart. Circ Res. 2007;100:489–501
- . Specific effects of n-3 fatty acids and 8-bromo-cGMP on the cyclic nucleotide phosphodiesterase activity in neonatal rat cardiac myocytes. J Mol Cell Cardiol. 1996;28:2151–2161
- . Inhibition of the different phosphodiesterase isoforms of rat heart cytosol by free fatty acids. J Cardiovasc Pharmacol. 1993;21:522–529
- . Opposite effects of cyclic GMP and cyclic AMP on Ca2+ current in single heart cells. Nature. 1986;323:273–275
- . Pharmacological and physiological significance of ion channels and factors that modulate them in vascular tissues. Pharmacol Rev. 1995;47:387–573
- . Modulation of ion channels by protein phosphorylation and dephosphorylation. Annu Rev Physiol. 1994;56:193–212
- . Regulation and modulation of calcium channels in cardiac, skeletal, and smooth muscle cells. Physiol Rev. 1994;74:365–507
- . Tyrosine kinase-dependent modulation of calcium entry in rabbit colonic muscularis mucosae. Am J Physiol. 1996;270:C1780–C1789
- . Tyrosine kinase inhibitors suppress agonist-induced contraction in smooth muscle. Biochem Biophys Res Commun. 1993;190:968–974
- . Modulation of voltage-dependent Ca2+ channels in rabbit colonic smooth muscle cells by c-Src and focal adhesion kinase. J Biol Chem. 1998;273:5337–5342
- . Inhibition of cytokine signaling in human retinal endothelial cells through modification of caveolae/lipid rafts by docosahexaenoic acid. Invest Ophthalmol Vis Sci. 2007;48:18–26
- . Angiotensin II activates pp60c-src in vascular smooth muscle cells. Circ Res. 1995;77:1053–1059
- . Association between the PDGF receptor and members of the src family of tyrosine kinases. Cell. 1990;62:481–492
- . Src family protein tyrosine kinases: cooperating with growth factor and adhesion signaling pathways. Curr Opin Cell Biol. 1997;9:187–192
- HRas-dependent pathways can activate morphological and genetic markers of cardiac muscle cell hypertrophy. [published erratum appears in J Biol Chem 1993 Jul 25;268(21):16082] J Biol Chem. 1993;268:2244–2249
- Ras-dependent pathways induce obstructive hypertrophy in echo-selected transgenic mice. Proc Natl Acad Sci U S A. 1997;94:4710–4715
- . Ventricular expression of a MLC-2v-ras fusion gene induces cardiac hypertrophy and selective diastolic dysfunction in transgenic mice. J Biol Chem. 1995;270:23173–23178
- . Inhibition of phenylephrine-induced cardiac hypertrophy by docosahexaenoic acid. J Cell Biochem. 2004;92:1141–1159
- . The Raf-MEK-ERK cascade represents a common pathway for alteration of intracellular calcium by Ras and protein kinase C in cardiac myocytes. J Biol Chem. 1998;273:21730–21735
- Mechanical loading stimulates cell hypertrophy and specific gene expression in cultured rat cardiac myocytes. Possible role of protein kinase C activation. J Biol Chem. 1991;266:1265–1268
- Stretching cardiac myocytes stimulates protooncogene expression. J Biol Chem. 1990;265:3595–3598
- . Mitogen-activated protein kinases mediate changes in gene expression, but not cytoskeletal organization associated with cardiac muscle cell hypertrophy. J Cell Biol. 1994;126:1565–1572
- . Hypoxia and hypoxia/reoxygenation activate Raf-1, mitogen-activated protein kinase kinase, mitogen-activated protein kinases, and S6 kinase in cultured rat cardiac myocytes. Circ Res. 1996;78:82–90
- . The MAPK signaling cascade. FASEB J. 1995;9:726–735
- Mechanical loading activates mitogen-activated protein kinase and S6 peptide kinase in cultured rat cardiac myocytes. J Biol Chem. 1993;268:12069–12076
- . Eicosapentaenoic acid suppressed the proliferation of vascular smooth muscle cells through modulation of binding of growth factor. Jpn J Pharmacol. 1992;58(Suppl 2):286
- . The biology of platelet-derived growth factor. Cell. 1986;46:155–169
- Omega-3 polyunsaturated fatty acids inhibit migration of human vascular smooth muscle cells in vitro. Life Sci. 1997;61:PL269–PL274
- . The complexity of Raf-1 regulation. Curr Opin Cell Biol. 1997;9:174–179
- . Regulation of Raf-1 kinase by interaction with the lipid second messenger, phosphatidic acid. Biochem Soc Trans. 1997;25:561–565
- . Rho is required for Galphaq and alpha1-adrenergic receptor signaling in cardiomyocytes. Dissociation of Ras and Rho pathways. J Biol Chem. 1996;271:31185–31190
- . Rho GTPases and signaling networks. Genes Dev. 1997;11:2295–2322
- Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho. EMBO J. 1996;15:2208–2216
- . A novel serine/threonine kinase binding the Ras-related RhoA GTPase which translocates the kinase to peripheral membranes. J Biol Chem. 1995;270:29051–29054
- Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase). [see comment] Science. 1996;273:245–248
- Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase). J Biol Chem. 1996;271:20246–20249
- Involvement of rho p21 in the GTP-enhanced calcium ion sensitivity of smooth muscle contraction. J Biol Chem. 1992;267:8719–8722
- Rho-associated kinase directly induces smooth muscle contraction through myosin light chain phosphorylation. J Biol Chem. 1997;272:12257–12260
- . Post-translational modifications of p21rho proteins. J Biol Chem. 1992;267:20033–20038
- . Protein kinase C in cardiac disease and as a potential therapeutic target. Cardiol Rev. 2005;13:3–12
- . Protein kinase cascades in the regulation of cardiac hypertrophy. J Clin Invest. 2005;115:527–537
- . Protein kinase C and myocardial biology and function. Circ Res. 2000;86:1104–1106
- . Increased endothelial albumin permeability mediated by protein kinase C activation. J Clin Invest. 1990;85:1991–1998
- . Expression of genes related to the extracellular matrix in human endothelial cells. Differential modulation by elevated glucose concentrations, phorbol esters, and cAMP. J Biol Chem. 1991;266:14244–14250
- Effects of forskolin and phorbol-myristate-acetate on cytoskeleton, extracellular matrix and protein phosphorylation in human endothelial cells. J Mol Cell Cardiol. 1989;21(Suppl 1):3–11
- Ets-1 upregulates matrix metalloproteinase-1 expression through extracellular matrix adhesion in vascular endothelial cells. Biochem Biophys Res Commun. 2002;291:130–138
- Cyclic stretch upregulates production of interleukin-8 and monocyte chemotactic and activating factor/monocyte chemoattractant protein-1 in human endothelial cells. Arterioscler Thromb Vasc Biol. 1998;18:894–901
- . Transcriptional and post-transcriptional regulation of monocyte chemoattractant protein-3 gene expression in human endothelial cells by phorbol ester and cAMP signalling. Immunology. 2000;99:561–568
- . Cytosolic Ca2+, Na+/H+ antiport, protein kinase C trio in essential hypertension. Am J Hypertens. 1994;7:205–212
- . Expression of protein kinase C beta in the heart causes hypertrophy in adult mice and sudden death in neonates. J Clin Invest. 1997;100:2189–2195
- Two distinct mechanisms mediate a differential regulation of protein kinase C isozymes in acute and prolonged myocardial ischemia. Circ Res. 1999;85:77–87
- Cardiotrophic effects of protein kinase C epsilon: analysis by in vivo modulation of PKCepsilon translocation. [see comment] Circ Res. 2000;86:1173–1179
- . Signal transduction during cardiac hypertrophy: the role of G alpha q, PLC beta I, and PKC. Cardiovasc Res. 1999;44:5–9
- . Protein kinase C isoform-selective signals that lead to cardiac hypertrophy and the progression of heart failure. Mol Cell Biochem. 2003;251:97–101
- . Protein kinase C isoform diversity in the heart. J Mol Cell Cardiol. 1995;27:141–153
- . Localization of protein kinases by anchoring proteins: a theme in signal transduction. Science. 1995;268:247–251
- . The extended protein kinase C superfamily. Biochem J. 1998;332:281–292
- . Differential activation of p70 and p85 S6 kinase isoforms during cardiac hypertrophy in the adult mammal. J Biol Chem. 1998;273:24610–24619
- . Eicosapentaenoic acid inhibits Ca2+ mobilization and PKC activity in vascular smooth muscle cells. Am J Hypertens. 2003;16:708–714
- . Docosahexaenoic acid inhibits protein kinase C translocation/activation and cardiac hypertrophy in rat cardiomyocytes. J Mol Genet Med. 2005;1:18–25
- . Fatty acids and cell signal transduction. J Lipid Mediators Cell Signal. 1994;9:91–116
- . Diacylglycerol fatty acid composition is related to activation of protein kinase C in cultured cardiomyocytes. Cardioscience. 1992;3:251–255
- Dietary fish oil attenuates cardiac hypertrophy in lipotoxic cardiomyopathy due to systemic carnitine deficiency. [see comment] Cardiovasc Res. 2005;68:213–223
- . Eicosapentaenoic acid suppressed the proliferation of vascular smooth muscle cells through modulation of various steps of growth signals. Lipids. 1996;31(Suppl):S301–S304
- . Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science. 1992;258:607–614
- . A potential second messenger role for unsaturated fatty acids: activation of Ca2+-dependent protein kinase. Science. 1984;224:622–625
- . Effects of dipalmitoylglycerol and fatty acids on membrane structure and protein kinase C activity. Biophys J. 1997;73:2603–2614
- . Signal transduction by the phosphatidylinositol cycle in myocardium. J Mol Cell Cardiol. 1995;27:93–106
- . Action of long-chain fatty acids on protein kinase C activity: comparison of omega-6 and omega-3 fatty acids. Anticancer Res. 1992;12:975–980
- . Fish intake and serum fatty acid profiles from freshwater fish. Am J Clin Nutr. 2006;84:1299–1307
- Discrepancies in dietary intakes and plasma concentrations of fatty acids according to age among Japanese female dietitians. Eur J Clin Nutr. 2002;56:524–531
- Dietary docosahexaenoic acid increases cerebral acetylcholine levels and improves passive avoidance performance in stroke-prone spontaneously hypertensive rats. Pharmacol Biochem Behav. 1997;58:1123–1129
PII: S0955-2863(07)00165-9
doi: 10.1016/j.jnutbio.2007.07.001
© 2008 Elsevier Inc. All rights reserved.
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The Journal of Nutritional Biochemistry
Volume 19, Issue 7
, Pages 417-437
, July 2008
