The Journal of Nutritional Biochemistry
Volume 18, Issue 12 , Pages 832-838 , December 2007

All-trans retinoic acid regulates c-jun expression via ERK5 in cardiac myoblasts

  • Xia Ren

      Affiliations

    • Laboratory of Development Molecular Biology, Department of Nutrition and Food Hygiene, School of Public Health, Peking University Health Science Center, Beijing 100083, PR China
  • ,
  • Xi Ma

      Affiliations

    • Laboratory of Medical Immunology, School of Basic Medical Science, Peking University Health Science Center, Beijing 100083, PR China
  • ,
  • Yong Li

      Affiliations

    • Laboratory of Development Molecular Biology, Department of Nutrition and Food Hygiene, School of Public Health, Peking University Health Science Center, Beijing 100083, PR China
    • Corresponding Author InformationCorresponding author. Fax: +86 10 82801177.

Received 15 October 2006 ,Revised 15 December 2006 ,Accepted 28 December 2006.

References 

  1. Moreno-Manzano V, Ishikawa Y, Lucio-Cazana J, Kitamura M. Suppression of apoptosis by all-trans-retinoic acid. Dual intervention in the c-Jun n-terminal kinase-AP-1 pathway. J Biol Chem. 1999;274:20251–20258
  2. Kim KN, Pie JE, Park JH, Park YH, Kim HW, Kim MK. Retinoic acid and ascorbic acid act synergistically in inhibiting human breast cancer cell proliferation. J Nutr Biochem. 2006;17:454–462
  3. Malik MA, Blusztajn JK, Greenwood CE. Nutrients as trophic factors in neurons and the central nervous system: role of retinoic acid. J Nutr Biochem. 2000;11:2–13
  4. Chen TH, Chang TC, Kang JO, Choudhary B, Makita T, Tran CM, et al. Epicardial induction of fetal cardiomyocyte proliferation via a retinoic acid-inducible trophic factor. Dev Biol. 2002;250:198–207
  5. Collop AH, Broomfield JA, Chandraratna RA, Yong Z, Deimling SJ, Kolker SJ, et al. Retinoic acid signaling is essential for formation of the heart tube in Xenopus. Dev Biol. 2006;291:96–109
  6. Ketley NJ, Allen PD, Kelsey SM, Newland AC. Modulation of idarubicin-induced apoptosis in human acute myeloid leukemia blasts by all-trans retinoic acid, 1,25(OH)2 vitamin D3, and granulocyte-macrophage colony-stimulating factor. Blood. 1997;90:4578–4587
  7. Johnson NL, Gardner AM, Diener KM, Lange-Carter CA, Gleavy J, Jarpe MB, et al. Signal transduction pathways regulated by mitogen-activated/extracellular response kinase kinase kinase induce cell death. J Biol Chem. 1996;271:3229–3237
  8. Katagiri C, Negishi K, Hibino T. c-JUN N-terminal kinase-1 (JNK1) but not JNK2 or JNK3 is involved in UV signal transduction in human epidermis. J Dermatol Sci. 2006;43:171–179
  9. Lewis TS, Shapiro PS, Ahn NG. Signal transduction through MAP kinase cascades. Adv Cancer Res. 1998;74:49–139
  10. Verheij M, Bose R, Lin XH, Yao B, Jarvis WD, Grant S, et al. Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis. Nature. 1996;380:75–79
  11. Venuprasad K, Elly C, Gao M, Salek-Ardakani S, Harada Y, Luo JL, et al. Convergence of itch-induced ubiquitination with MEKK1-JNK signaling in Th2 tolerance and airway inflammation. J Clin Invest. 2006;116:1117–1126
  12. Pearson G, Robinson F, Beers Gibson T, Xu BE, Karandikar M, Berman K, et al. Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr Rev. 2001;22:153–183
  13. Zhou G, Bao ZQ, Dixon JE. Components of a new human protein kinase signal transduction pathway. J Biol Chem. 1995;270:12665–12669
  14. Coso OA, Montaner S, Fromm C, Lacal JC, Prywes R, Teramoto H, et al. Signaling from G protein-coupled receptors to the c-jun promoter involves the MEF2 transcription factor. Evidence for a novel c-jun amino-terminal kinase-independent pathway. J Biol Chem. 1997;272:20691–20697
  15. Karin M, Liu Z, Zandi E. AP-1 function and regulation. Curr Opin Cell Biol. 1997;9:240–246
  16. Zhao M, Liu Y, Bao M, Kato Y, Han J, Eaton JW. Vascular smooth muscle cell proliferation requires both p38 and BMK1 MAP kinases. Arch Biochem Biophys. 2002;400:199–207
  17. Simonson MS. Anti-AP-1 activity of all-trans retinoic acid in glomerular mesangial cells. Am J Physiol. 1994;267:F805–F815
  18. Gupta A, Aberle NS, Ren J, Sharma AC. Endothelin-converting enzyme-1-mediated signaling in adult rat ventricular myocyte contractility and apoptosis during sepsis. J Mol Cell Cardiol. 2005;38:527–537
  19. Lee WS, Liu CW, Juan SH, Liang YC, Ho PY, Lee YH. Molecular mechanism of progesterone-induced antiproliferation in rat aortic smooth muscle cells. Endocrinology. 2003;144:2785–2790
  20. Zhao M, New L, Kravchenko VV, Kato Y, Gram H, di Padova F, et al. Regulation of the MEF2 family of transcription factors by p38. Mol Cell Biol. 1999;19:21–30
  21. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72:248–254
  22. Desai SH, Niles RM. Characterization of retinoic acid-induced AP-1 activity in B16 mouse melanoma cells. J Biol Chem. 1997;272:12809–12815
  23. Schule R, Rangarajan P, Yang N, Kliewer S, Ransone LJ, Bolado J, et al. Retinoic acid is a negative regulator of AP-1-responsive genes. Proc Natl Acad Sci U S A. 1991;88:6092–6096
  24. Kato Y, Kravchenko VV, Tapping RI, Han J, Ulevitch RJ, Lee JD. BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C. Embo J. 1997;16:7054–7066
  25. Kato Y, Tapping RI, Huang S, Watson MH, Ulevitch RJ, Lee JD. Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor. Nature. 1998;395:713–716
  26. Kayahara M, Wang X, Tournier C. Selective regulation of c-jun gene expression by mitogen-activated protein kinases via the 12-o-tetradecanoylphorbol-13-acetate-responsive element and myocyte enhancer factor 2 binding sites. Mol Cell Biol. 2005;25:3784–3792
  27. Lee JD, Ulevitch RJ, Han J. Primary structure of BMK1: a new mammalian map kinase. Biochem Biophys Res Commun. 1995;213:715–724
  28. Nishimoto S, Nishida E. MAPK signalling: ERK5 versus ERK1/2. EMBO Rep. 2006;7:782–786
  29. Kondoh K, Terasawa K, Morimoto H, Nishida E. Regulation of nuclear translocation of extracellular signal-regulated kinase 5 by active nuclear import and export mechanisms. Mol Cell Biol. 2006;26:1679–1690
  30. Esparis-Ogando A, Diaz-Rodriguez E, Montero JC, Yuste L, Crespo P, Pandiella A. Erk5 participates in neuregulin signal transduction and is constitutively active in breast cancer cells overexpressing ErbB2. Mol Cell Biol. 2002;22:270–285
  31. Buschbeck M, Ullrich A. The unique C-terminal tail of the mitogen-activated protein kinase ERK5 regulates its activation and nuclear shuttling. J Biol Chem. 2005;280:2659–2667
  32. Fukuda M, Gotoh Y, Nishida E. Interaction of MAP kinase with MAP kinase kinase: its possible role in the control of nucleocytoplasmic transport of MAP kinase. EMBO J. 1997;16:1901–1908

 Funding sources: National Natural Science Foundation No. 30371208, People's Republic of China.

PII: S0955-2863(07)00048-4

doi: 10.1016/j.jnutbio.2006.12.023

The Journal of Nutritional Biochemistry
Volume 18, Issue 12 , Pages 832-838 , December 2007