The Journal of Nutritional Biochemistry
Volume 18, Issue 12 , Pages 820-826 , December 2007

Dietary supplementation with zinc oxide decreases expression of the stem cell factor in the small intestine of weanling pigs

  • Deyuan Ou

      Affiliations

    • National Key Laboratory of Animal Nutrition, China Agricultural University, Beijing 100094, PR China
  • ,
  • Defa Li

      Affiliations

    • National Key Laboratory of Animal Nutrition, China Agricultural University, Beijing 100094, PR China
    • Corresponding Author InformationCorresponding authors. Tel.: +1 979 845 1817; fax: +1 979 845 6057.
  • ,
  • Yunhe Cao

      Affiliations

    • National Key Laboratory of Animal Nutrition, China Agricultural University, Beijing 100094, PR China
  • ,
  • Xilong Li

      Affiliations

    • National Key Laboratory of Animal Nutrition, China Agricultural University, Beijing 100094, PR China
  • ,
  • Jingdong Yin

      Affiliations

    • National Key Laboratory of Animal Nutrition, China Agricultural University, Beijing 100094, PR China
    • Corresponding Author InformationCorresponding authors. Tel.: +1 979 845 1817; fax: +1 979 845 6057.
  • ,
  • Shiyan Qiao

      Affiliations

    • National Key Laboratory of Animal Nutrition, China Agricultural University, Beijing 100094, PR China
  • ,
  • Guoyao Wu

      Affiliations

    • Department of Animal Science, Texas A&M University, College Station, TX 77843, USA
    • Corresponding Author InformationCorresponding authors. Tel.: +1 979 845 1817; fax: +1 979 845 6057.

Received 7 August 2006 ,Revised 2 December 2006 ,Accepted 28 December 2006.

References 

  1. Bhutta ZA, Ghishan F, Lindley K, Memon IA, Mittal S, Rhoads JM. Persistent and chronic diarrhea and malabsorption: working group report of the second World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition. J Pediatr Gastroenterol Nutr. 2004;39:S711–S716
  2. Brown KH. Diarrhea and malnutrition. J Nutr. 2003;133:328S–332S
  3. Hill GM, Mahan DC, Carter SD, Cromwell GL, Ewan RC, Harrold RL, et al. NCR-42 Committee on Swine Nutrition. Effect of pharmacological concentrations of ZnO with or without the inclusion of an antibacterial agent on nursery pig performance. J Anim Sci. 2001;79:934–941
  4. Chandra RK. 1990 McCollum award lecture. Nutrition and immunity: lessons from the past and new insights into the future. Am J Clin Nutr. 1991;53:1087–1101
  5. Tran CD, Miller LV, Krebs NF, Lei S, Hambidge KM. Dietary supplementation with zinc and a growth factor extract derived from bovine cheese whey improves methotrexate-damaged rat intestine. Am J Clin Nutr. 2003;77:1296–1303
  6. Wu G, Jaeger LA, Bazer FW, Rhoads JM. Arginine deficiency in preterm infants: biochemical mechanisms and nutritional implications. J Nutr Biochem. 2004;15:442–451
  7. Wu G, Flynn NE, Knabe DA, Jaeger LA. A cortisol surge mediates the enhanced polyamine synthesis in porcine enterocytes during weaning. Am J Physiol Regul Integr Comp Physiol. 2000;279:R554–R559
  8. Marshall JS. Mast-cell responses to pathogens. Nat Rev Immunol. 2004;4:787–799
  9. Wershil BK, Furuta GT, Wang ZS, Galli SJ. Mast cell-dependent neutrophil and mononuclear cell recruitment in immunoglobulin E-induced gastric reactions in mice. Gastroenterology. 1996;110:1482–1490
  10. Qadri F, Bhuiyan TR, Dutta KK, Raqib R, Alam MS, Alam NH, et al. Acute dehydrating disease caused by Vibrio cholerae serogroups O1 and O139 induce increases in innate cells and inflammatory mediators at the mucosal surface of the gut. Gut. 2004;53:62–69
  11. Galli SJ. New insights into “the riddle of the mast cells”: microenvironmental regulation of mast cell development and phenotypic heterogeneity. Lab Invest. 1990;62:5–33
  12. Longley BJ, Morganroth GS, Tyrrell L, Ding TG, Anderson DM, Williams DE, et al. Altered metabolism of mast-cell growth factor (c-kit ligand) in cutaneous mastocytosis. N Engl J Med. 1993;328:1302–1307
  13. National Research Council . Nutrient Requirements of Swine. 10th ed. Washington, DC: National Academy Press; 1998;
  14. Swamy HVLN, Smith TK, MacDonald EJ. Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on brain regional neurochemistry of starter pigs and broiler chickens. J Anim Sci. 2004;82:2131–2139
  15. Enerback L. Mast cells in rat gastrointestinal mucosa. I. Effects of fixation. Acta Pathol Microbiol Scand. 1966;66:289–302
  16. Crowe SE, Luthra GK, Perduc MH. Mast cell mediated ion transport in intestine from patients with and without inflammatory bowel disease. Gut. 1997;41:785–792
  17. Veciana-Nogues MT, Hernandez-Jover T, Marine-Font A, Vidal-Carou MC. Liquid chromatographic method for determination of biogenic amines in fish and fish products. J AOAC Int. 1995;78:1045–1050
  18. Gaca MD, Pickering JA, Arthur MJ, Benyon RC. Human and rat hepatic stellate cells produce stem cell factor: a possible mechanism for mast cell recruitment in liver fibrosis. J Hepatol. 1999;30:850–858
  19. Stankiewicz M, Shaw RJ, Jonas WE, Cabaj W, Grimmett DJ, Douch PG. A technique for the isolation and purification of viable mucosal mast cells/globule leukocytes from the small intestine of parasitised sheep. Int J Parasitol. 1994;24:307–309
  20. Hambidge KM. Zinc and diarrhea. Acta Paediatr. 1992;381(Suppl):82–86
  21. Rodriguez P, Darmon N, Chappuis P, Candalh C, Blaton MA, Bouchaud C, et al. Intestinal paracellular permeability during malnutrition in guinea pigs: effect of high dietary zinc. Gut. 1996;39:416–422
  22. Sazawal S, Black RE, Bhan MK, Bhandari N, Sinha A, Jalla S. Zinc supplementation in young children with acute diarrhea in India. N Engl J Med. 1995;333:839–844
  23. Shamir R, Makhoul IR, Etzioni A, Shehadeh N. Evaluation of a diet containing probiotics and zinc for the treatment of mild diarrhea illness in children younger than one year of age. J Am Coll Nutr. 2005;24:370–375
  24. Shankar AH, Prasad AS. Zinc and immune function: the biological basis of altered resistance to infection. Am J Clin Nutr. 1998;68(Suppl. 2):447–463
  25. Söderholm JD, Perduc MH. Stress and intestinal barrier function. Am J Physiol. 2001;280:G7–G13
  26. Santos J, Yang PC, Soderholm JD, Benjamin M, Perdue MH. Role of mast cells in chronic stress induced colonic epithelial barrier dysfunction in the rat. Gut. 2001;48:630–636
  27. Rangachari PK. Histamine: mercurial messenger in the gut. Am J Physiol. 1992;262:G1–G13
  28. Castro GA, Harari Y, Russell D. Mediators of anaphylaxis-induced ion transport changes in small intestine. Am J Physiol. 1987;253:G540–G548
  29. Brandt EB, Strait RT, Hershko D, Wang Q, Muntel EE, Scribner TA, et al. Mast cells are required for experimental oral allergen-induced diarrhea. J Clin Invest. 2003;112:1666–1677
  30. Wang YZ, Cooke HJ, Su HC, Fertel R. Histamine augments colonic secretion in guinea pig distal colon. Am J Physiol. 1990;258:G432–G439
  31. Cooke HJ, Nemeth PR, Wood JD. Histamine action on guinea pig ileal mucosa. Am J Physiol. 1984;246:G372–G377
  32. Wang YZ, Cooke HJ. H2 receptors mediate cyclical chloride secretion in guinea pig distil colon. Am J Physiol. 1990;258:G.887–G.893
  33. Kazimierczak W, Malinski C. The effect of zinc ions on selective and nonselective histamine release in vitro. Agents Actions. 1974;4:1–6
  34. Marone G, Columbo M, de Paulis A, Cirillo R, Giugliano R, Condorelli M. Physiological concentrations of zinc inhibit the release of histamine from human basophils and lung mast cells. Agents Actions. 1986;18:103–106
  35. Ghishan FK. Transport of electrolytes, water, and glucose in zinc deficiency. J Pediatr Gastroenterol Nutr. 1984;3:608–612
  36. Darmon N, Pelissier MA, Candalh C, Chappuis P, Blaton MA, Albrecht R, et al. Zinc and intestinal anaphylaxis to cow's milk proteins in malnourished guinea pigs. Pediatr Res. 1997;42:208–213
  37. Hoque KM, Rajendran VM, Binder HJ. Zinc inhibits cAMP-stimulated Cl secretion via basolateral K-channel blockade in rat ileum. Am J Physiol. 2005;288:G956–G963
  38. Bischoff SC, Dahinden CA. c-kit ligand: a unique potentiator of mediator release by human lung mast cells. J Exp Med. 1992;175:237–244
  39. Bischoff SC, Schwengberg S, Wordelmann K, Weimann A, Raab R, Manns MP. Effect of c-kit ligand, stem cell factor, on mediator release by human intestinal mast cells isolated from patients with inflammatory bowel disease and controls. Gut. 1996;38:104–114
  40. Welker P, Grabbe J, Gibbs B, Zuberbier T, Henz BM. Human mast cells produce and differentially express both soluble and membrane-bound stem cell factor. Scand J Immunol. 1999;49:495–500
  41. Karimi K, Redegeld FA, Heijdra B, Nijkamp FP. Stem cell factor and interleukin-4 induce murine bone marrow cells develop into mast cells with connective tissue type characteristics in vitro. Exp Hematol. 1999;27:654–662
  42. Pang X, Sant G, Theoharides TC. Altered expression of bladder mast cell growth factor receptor (c-kit) in interstitial cystitis. Urology. 1998;51:939–944
  43. Wu G. Intestinal mucosal amino acid catabolism. J Nutr. 1998;128:1249–1252
  44. Li X, Yin JD, Li DF, Chen XJ, Zang JJ, Zhou X. Dietary supplementation with zinc oxide increases IGF-I and IGF-II receptor gene expression in the small intestine of weanling pigs. J Nutr. 2006;136:1786–1791
  45. Wang JJ, Li DF, Dangott LJ, Wu GY. Proteomics and its role in nutrition research. J Nutr. 2006;136:1759–1762

PII: S0955-2863(07)00045-9

doi: 10.1016/j.jnutbio.2006.12.022

The Journal of Nutritional Biochemistry
Volume 18, Issue 12 , Pages 820-826 , December 2007