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The Journal of Nutritional Biochemistry
Volume 18, Issue 2
, Pages 75-85
, February 2007
Mercury as a risk factor for cardiovascular diseases
References
- . Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation. 2002;106:2747–2757
- . The three modern faces of mercury. Environ Health Perspect. 2002;110(Suppl. 1):11–23
- Water quality criterion for the protection of human health: methyl mercury. Washington (DC, USA): Environmental Protection Agency; 2001;
- . Heavy metal contents in Finnish sea and water fish. National Food Agency of Finland. Available at http://www.palvelu.fi/evi/files/55_519_301.pdf
- Mercury levels in commercial fish and shellfish. US Department of Health and Human Services and US Environmental Protection Agency. Updated February 2006; accessed March 2006; available at: http://www.cfsan.fda.gov/~frf/sea-mehg.html2001;
- . Neurotoxic and molecular effects of methylmercury in humans. Rev Environ Health. 2003;18:19–31
- . Environmental health criteria 101: methylmercury. Geneva (Switzerland): World Health Organization; 1990;
- . Toxicological effects of methylmercury. Washington (DC): National Academy Press; 2000;
- Mercury study report to Congress. Washington (DC): Environmental Protection Agency; 1997;
- What you need to know about mercury in fish and shellfish. US Food and Drug Administration and US Environmental Protection Agency. Accessed March 2006; available at http://www.epa.gov/waterscience/fishadvice/advice.html2004;
- . Mercury accumulation and accelerated progression of carotid atherosclerosis: a population-based prospective 4-year follow-up study in men in eastern Finland. Atherosclerosis. 2000;148:265–273
- Intake of mercury from fish, lipid peroxidation, and the risk of myocardial infarction and coronary, cardiovascular, and any death in eastern Finnish men. Circulation. 1995;91:645–655
- Mercury, fish oils, and risk of acute coronary events and cardiovascular disease, coronary heart disease, and all-cause mortality in men in eastern Finland. Arterioscler Thromb Vasc Biol. 2005;25:228–233
- Mercury, fish oils, and the risk of myocardial infarction. N Engl J Med. 2002;347:1747N–1754N
- . Is there a continuing need for longitudinal epidemiologic research? The Kuopio Ischaemic Heart Disease Risk Factor Study. Ann Clin Res. 1988;20:46–50
- . Fish oil-derived fatty acids, docosahexaenoic acid and docosapentaenoic acid, and the risk of acute coronary events: the Kuopio Ischaemic Heart Disease Risk Factor Study. Circulation. 2000;102:2677–2679
- Mercury and the risk of coronary heart disease in men. N Engl J Med. 2002;347:1755–1760
- Markers of high fish intake are associated with decreased risk of a first myocardial infarction. Br J Nutr. 2001;86:397–404
- . The importance of selenium to human health. Lancet. 2000;356:233–241
- . Mercury: selenium interactions and health implications. Seychelles Med Dental J. 2004;7:72–77
- . Selenium: relation to decreased toxicity of methylmercury added to diets containing tuna. Science. 1972;175:1122–1124
- . Correlation between selenium and mercury in man following exposure to inorganic mercury. Nature. 1975;254:238–239
- . Molecular interactions with mercury in the kidney. Pharmacol Rev. 2000;52:113–143
- Mercury-binding capacity of organic and inorganic selenium in rat blood and liver. Biol Trace Elem Res. 1998;65:197–210
- Effect of supplementation with organic selenium on mercury status as measured by mercury in pubic hair. J Trace Elem Med Biol. 2000;14:84–87
- . Atherosclerosis — an inflammatory disease. N Engl J Med. 1999;340:115–126
- . The oxidative modification hypothesis of atherogenesis: an overview. Free Radic Biol Med. 2000;28:1815–1826
- Elevated levels of oxidized low density lipoprotein show a positive relationship with the severity of acute coronary syndromes. Circulation. 2001;103:1955–1960
- Oxidized LDL in carotid plaques and plasma associates with plaque instability. Arterioscler Thromb Vasc Biol. 2002;22:1649–1654
- . Role of monocytes in atherogenesis. Physiol Rev. 2003;83:1069–1112
- Circulating oxidized low-density lipoprotein and common carotid artery intima–media thickness in a random sample of middle-aged men. J Biomed Sci. 2004;11:356–361
- . Circulating oxidized LDL is associated with subclinical atherosclerosis development and inflammatory cytokines (AIR study). Arterioscler Thromb Vasc Biol. 2002;22:1162–1167
- . Oxidized low-density lipoprotein in plasma is a prognostic marker of subclinical atherosclerosis development in clinically healthy men. J Intern Med. 2004;256:413–420
- . Circulating oxidized low-density lipoprotein and its association with carotid intima–media thickness in asymptomatic members of familial combined hyperlipidemia families. Arterioscler Thromb Vasc Biol. 2004;24:1492–1497
- Circulating oxidized low density lipoprotein levels. A biochemical risk marker for coronary heart disease. Arterioscler Thromb Vasc Biol. 2000;20:2243–2247
- . Free radicals, antioxidants, and nutrition. Nutrition. 2002;18:872–879
- . The mechanism of action of antioxidants against lipoprotein peroxidation, evaluation based on kinetic experiments. Prog Lipid Res. 2002;41:279–314
- . Role of oxidative modifications in atherosclerosis. Physiol Rev. 2004;84:1381–1478
- . Lipid peroxidation in rats administrated with mercuric chloride. Biol Trace Elem Res. 1996;52:193–206
- . Lipid peroxidation in liver of rats administrated with methyl mercuric chloride. Biol Trace Elem Res. 1996;54:33–41
- Methylmercury cytotoxicity in PC12 cells is mediated by primary glutathione depletion independent of excess reactive oxygen species generation. Toxicology. 2004;204:175–185
- . Nutritional biochemistry of cellular glutathione. J Nutr Biochem. 1997;8:660–672
- . Melatonin protects against mercury(II)-induced oxidative tissue damage in rats. Pharmacol Toxicol. 2003;93:290–296
- . Behavior of methylmercury in mammalian erythrocytes. Toxicol Appl Pharmacol. 1980;54:405–410
- . Paraoxonase 1 and atherosclerosis: is the gene or the protein more important?. Free Radic Biol Med. 2004;37:1317–1323
- . Inhibition of paraoxonase activity in human liver microsomes by exposure to EDTA, metals and mercurials. Chem Biol Interact. 1997;105:169–179
- . The glutathione peroxidases. Cell Mol Life Sci. 2000;57:1825–1835
- . Glutathione peroxidase. Basic Life Sci. 1988;49:663–668
- Diversity of glutathione peroxidases. Methods Enzymol. 1995;252:38–53
- . Comparative study of the enzymatic defense systems against oxygen-derived free radicals: the key role of glutathione peroxidase. Free Radic Biol Med. 1987;3:3–7
- . Effect of selenium deficiency on hydroperoxide-induced glutathione release from the isolated perfused rat heart. J Nutr. 1985;115:733–742
- Glutathione peroxidase 1 activity and cardiovascular events in patients with coronary artery disease. N Engl J Med. 2003;349:1605–1613
- . Methylmercury-induced neurotoxicity in cerebral neuron culture is blocked by antioxidants and NMDA receptor antagonists. Neurotoxicology. 1996;17:37–45
- . The protective effect of vitamin E and N,N′-diphenyl-p-phenylenediamine (DPPD) against methyl mercury toxicity in the rat. J Nutr. 1979;109:1673–1681
- . Antioxidant compounds and Ca(2+) pathway blockers differentially protect against methylmercury and mercuric chloride neurotoxicity. J Neurosci Res. 2001;66:135–145
- . Interactions of vitamin E and selenium with mercury and silver. Ann N Y Acad Sci. 1980;355:212–226
- . Stimulating effects of mercuric- and silver ions on the superoxide anion production in human polymorphonuclear leukocytes. Free Radic Res Commun. 1993;18:87–98
- . Reactivity of Hg(II) with superoxide: evidence for the catalytic dismutation of superoxide by Hg(II). J Biochem Toxicol. 1991;6:293–298
- . Mercury-induced H2O2 production and lipid peroxidation in vitro in rat kidney mitochondria. Biochem Pharmacol. 1991;42 Suppl:S181–S187
- . Studies on Hg(II)-induced H2O2 formation and oxidative stress in vivo and in vitro in rat kidney mitochondria. Biochem Pharmacol. 1993;45:2017–2024
- . Mercuric compounds inhibit human monocyte function by inducing apoptosis: evidence for formation of reactive oxygen species, development of mitochondrial membrane permeability transition and loss of reductive reserve. Toxicology. 1997;124:211–224
- . Does mercury promote lipid peroxidation? An in vitro study concerning mercury, copper, and iron in peroxidation of low-density lipoprotein. Biol Trace Elem Res. 2004;101:117–132
- . Prenatal methylmercury exposure as a cardiovascular risk factor at seven years of age. Epidemiology. 1999;10:370–375
- . Cardiac autonomic activity in methylmercury neurotoxicity: 14-year follow-up of a Faroese birth cohort. J Pediatr. 2004;144:169–176
- Autonomic nervous functions in fetal type Minamata disease patients: assessment of heart rate variability. Tohoku J Exp Med. 2003;198:215–221
- . Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med. 1997;336:1066–1071
- . Au(III), Pd(II), Ni(II), and Hg(II) alter NF kappa B signaling in THP1 monocytic cells. J Biomed Mater Res A. 2005;74:474–481
- . Mercuric ion attenuates nuclear factor-kappaB activation and DNA binding in normal rat kidney epithelial cells: implications for mercury-induced nephrotoxicity. Toxicol Appl Pharmacol. 2001;173:176–187
- . Inhibition of NF-kappa B binding to DNA by chromium, cadmium, mercury, zinc, and arsenite in vitro: evidence of a thiol mechanism. Arch Biochem Biophys. 1998;349:356–362
- Minimal immunological effects on workers with prolonged low exposure to inorganic mercury. Occup Environ Med. 1997;54:437–442
- . Minor effects of low exposure to inorganic mercury on the human immune system. Scand J Work Environ Health. 1993;19:405–413
- . Role of transcription factor NF-kappa B/rel in induction of nitric oxide synthase. J Biol Chem. 1994;269:4705–4708
- . Nitric oxide: pathophysiological mechanisms. Annu Rev Physiol. 1995;57:737–769
- . Mercury inhibits nitric oxide production but activates proinflammatory cytokine expression in murine macrophage: differential modulation of NF-kappaB and P38 MAPK signaling pathways. Nitric Oxide. 2002;7:67–74
- Endogenous nitric oxide synthase inhibitor: a novel marker of atherosclerosis. Circulation. 1999;99:1141–1146
- Acute elevations of plasma asymmetric dimethylarginine and impaired endothelial function in response to a high-fat meal in patients with type 2 diabetes. Arterioscler Thromb Vasc Biol. 2000;20:2039–2044
- Risk of acute coronary events and serum concentration of asymmetrical dimethylarginine. Lancet. 2001;358:2127–2128
- Plasma concentration of asymmetrical dimethylarginine and mortality in patients with end-stage renal disease: a prospective study. Lancet. 2001;358:2113–2117
- . S-nitrosylation of dimethylarginine dimethylaminohydrolase regulates enzyme activity: further interactions between nitric oxide synthase and dimethylarginine dimethylaminohydrolase. Proc Natl Acad Sci U S A. 2002;99:13527–13532
- . The pathogenesis of atherosclerosis (first of two parts). N Engl J Med. 1976;295:369–377
- . The pathogenesis of atherosclerosis (second of two parts). N Engl J Med. 1976;295:420–425
- . Endothelial regeneration: III. Time course of intimal changes after small defined injury to rat aortic endothelium. Lab Invest. 1981;44:301–308
- . In vitro reendothelialization of a single-cell wound. Role of microfilament bundles in rapid lamellipodia-mediated wound closure. Lab Invest. 1984;51:75–81
- . Inhibitory effect of methylmercury on migration and tube formation by cultured human vascular endothelial cells. Arch Toxicol. 1995;69:357–361
- . Low doses of heavy metals disrupt normal structure and function of rat platelets. J Environ Pathol Toxicol Oncol. 2001;20:65–75
- . In vitro binding of inorganic mercury to the plasma membrane of rat platelet affects Na+–K+-ATPase activity and platelet aggregation. Biometals. 2002;15:51–57
- . In vitro toxicity of mercury, cadmium, and arsenic to platelet aggregation: influence of adenylate cyclase and phosphodiesterase activity. In Vitro Mol Toxicol. 2000;13:137–144
- . Disorders in blood coagulation in humans occupationally exposed to mercuric vapors. J Trace Elem Exp Med. 2002;15:21–29
- Block of sodium channels by divalent mercury: role of specific cysteinyl residues in the p-loop region. Biophys J. 2000;79:1336–1345
- Effect of sulfhydryl oxidoreduction on permeability of cardiac tetrodotoxin-insensitive sodium channel. Life Sci. 1998;63:1023–1035
- A quantitative risk–benefit analysis of changes in population fish consumption. Am J Prev Med. 2005;29:325–334
- . Decline in fish consumption among pregnant women after a national mercury advisory. Obstet Gynecol. 2003;102:346–351
☆ All listed authors contributed to this work, and all authors agreed to submit this manuscript to the Journal of Nutritional Biochemistry. No part of this work has been published before, except in abstract form, and all human and animal studies have been reviewed by the appropriate ethics committees.
☆☆ This work was supported by the Finnish Cultural Foundation and the Yrjö Jahnsson Foundation (for J.K. Virtanen).
PII: S0955-2863(06)00100-8
doi: 10.1016/j.jnutbio.2006.05.001
© 2007 Elsevier Inc. All rights reserved.
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The Journal of Nutritional Biochemistry
Volume 18, Issue 2
, Pages 75-85
, February 2007
