The Journal of Nutritional Biochemistry
Volume 16, Issue 7 , Pages 385-397, July 2005

β-Carotene breakdown products may impair mitochondrial functions — potential side effects of high-dose β-carotene supplementation☆

  • Werner Siems

      Affiliations

    • Loges-School for Physical Medicine and Rehabilitation, D-38667 Bad Harzburg, Germany
    • Corresponding Author InformationCorresponding author. Tel.: +49 5322 2541; fax: +49 5322 54150.
    • ,
  • Ingrid Wiswedel

      Affiliations

    • Department of Biochemical Pathobiochemistry, Institute of Biochemistry and Clinical Pathobiochemistry, Otto-von-Guericke University Magdeburg, D-39120 Magdeburg, Germany
    • ,
  • Costantino Salerno

      Affiliations

    • Laboratory of Clinical Biochemistry, University of Rome La Sapienza, I-00185 Rome, Italy
    • ,
  • Carlo Crifò

      Affiliations

    • Department of Biochemical Sciences, University of Rome La Sapienza, I-00185 Rome, Italy
    • ,
  • Wolfgang Augustin

      Affiliations

    • Department of Biochemical Pathobiochemistry, Institute of Biochemistry and Clinical Pathobiochemistry, Otto-von-Guericke University Magdeburg, D-39120 Magdeburg, Germany
    • ,
  • Lorenz Schild

      Affiliations

    • Department of Biochemical Pathobiochemistry, Institute of Biochemistry and Clinical Pathobiochemistry, Otto-von-Guericke University Magdeburg, D-39120 Magdeburg, Germany
    • ,
  • Claus-Dieter Langhans

      Affiliations

    • Department of Paediatrics, University of Heidelberg, D-69120 Heidelberg, Germany
    • ,
  • Olaf Sommerburg

      Affiliations

    • Department of Paediatrics, University of Ulm, D-89077 Ulm, Germany

Received 12 February 2004; received in revised form 1 December 2004; accepted 12 January 2005.

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☆ The investigations were supported by grants from the University of Ulm, Ulm, Germany (to OS), and from BASF Aktiengesellschaft, Ludwigshafen, Germany (to WS).

PII: S0955-2863(05)00025-2

doi:10.1016/j.jnutbio.2005.01.009

The Journal of Nutritional Biochemistry
Volume 16, Issue 7 , Pages 385-397, July 2005

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